Outcome in RDC schizo-affective depression: the importance of diagnostic subtyping |
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| Authors: | W Coryell W Grove M vanEerdewegh M Keller J Endicott |
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| Affiliation: | 1. Centre for Studies on Justice and Society, Institute of Sociology, Pontificia Universidad Católica de Chile, Santiago, Chile;2. Early Intervention Program, Instituto Psiquiátrico Dr J. Horwitz Barak, Santiago, Chile;3. Department of Psychiatry, Pontificia Universidad Católica de Chile, Santiago, Chile;4. Escuela de Gobierno, Pontificia Universidad Católica de Chile, Santiago, Chile;5. Research Center for Integrated Disaster Risk Management (CIGIDEN), Santiago, Chile;6. CIFAR Azrieli Global Scholars program, CIFAR, Toronto, Canada;7. Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Santiago, Chile;8. Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King''s College London, London, UK;9. Department of Neurology and Psychiatry, Clinica Alemana Universidad Del Desarrollo, Santiago, Chile;1. Department of Psychiatry, McGill University, Montréal, Canada;2. Prevention and Early Intervention Program for Psychosis, Douglas Mental Health University Institute, Montréal, Canada;3. Department of Psychology, University of Konstanz, Konstanz, Germany |
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| Abstract: | A 2-year semiannual follow-up of 40 patients with RDC schizo-affective disorder, depressed type revealed poorer outcomes among those who were subtyped as chronic or mainly schizophrenic patients than among their counterparts with nonchronic or mainly affective schizo-affective depression. Outcomes for these latter groups, in turn, were no worse than those for patients with psychotic major depression. Among a variety of predictors entered into step-wise regression analyses, diagnosis was most important in predicting recovery overall and outcome at 6 months, while demographic variables, particularly sex, predicted outcome at 2 years. |
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