| 神经节苷脂治疗126例急性脑梗死的疗效观察 |
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| 引用本文： | 李卫东,李红桃,杜迎春. 神经节苷脂治疗126例急性脑梗死的疗效观察[J]. 国外医学:老年医学分册, 2010, 31(1): 4-5 |
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| 作者姓名： | 李卫东 李红桃 杜迎春 |
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| 作者单位： | 河南省平顶山市第一人民医院神经内科,平顶山,467000,中国 |
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| 摘 要： | 目的：观察神经节苷脂治疗急性脑梗死的有效性和安全性。方法：将126例急性脑梗死患者随机分为神经节苷脂组和对照组，在常规治疗的基础上，分别采用神经节苷脂40mg或胞二磷胆碱0．75mg加入生理盐水中静脉滴注，每日1次，共2周；观察两组患者治疗前后神经功能缺损程度评分及日常生活活动量表评分的变化及不良反应。结果：治疗后神经节苷脂组和对照组神经功能缺损程度评分及日常生活活动量表评分与治疗前相比均有显著改善（P〈0．05～0．01）；且神经节苷脂组神经功能缺损程度评分优于对照组，神经节苷脂组日常生活活动量表评分明显高于照组，相比差异显著（均P〈0．01）。两组均未发现明显不良反应。结论：神经节苷脂能减轻急性脑梗死后神经元的损伤，具有脑保护作用。
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| 关 键 词： | 脑梗死 神经节苷脂 治疗疗效 |
Efficacy of Ganglioside in the Treatment of One Hundred and Twenty-six Older Adults with Acute Cerebral Infarction |
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| Li Weidong Li Hongtao Du Yingchun. Efficacy of Ganglioside in the Treatment of One Hundred and Twenty-six Older Adults with Acute Cerebral Infarction[J]. Foreign Medical Sciences(Geriatrics), 2010, 31(1): 4-5 |
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| Authors: | Li Weidong Li Hongtao Du Yingchun |
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| Affiliation: | Li Weidong Li Hongtao Du Yingchun Department of Neurology,the First People's Hospital,Pingdingshan 467000,China |
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| Abstract: | OBJECTIVE:To evaluate the efficacy and safety of ganglioside(GM1)in the treatment of older adults with acute cere-bral infarction.METHODS:I26 patients with acute cerebral infarction were randomly divided into GM1 group and control group.Based on routine treatments,they received GM1(40mg,once a day)or Citicoline(0.75mg,once a day).The duration of treatment in each group was 2 weeks.The Neurological Deficit Scores(NDS)and Activities of Daily Living(ADL)were used.And NDS score,ADL score and adverse reaction be... |
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| Keywords: | Cerebral infarction Gangliosides Treatment outcome |
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