| CT与全身核素骨显像联合诊断单发骨转移瘤 |
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| 引用本文： | 王建方,赵新明,张敬勉,王颖晨,张召奇,李德志,孙莉,戴春暖.CT与全身核素骨显像联合诊断单发骨转移瘤[J].中国医学影像技术,2011,27(3):594-598. |
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| 作者姓名： | 王建方 赵新明 张敬勉 王颖晨 张召奇 李德志 孙莉 戴春暖 |
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| 作者单位： | 河北医科大学第四医院核医学科,河北,石家庄,050011 |
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| 基金项目： | 河北省普通高等学校强势特色学科肿瘤学组(冀教高2005[52])、河北省卫生厅科研基金(20100424)。 |
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| 摘 要： | 目的 评价全身骨显像、CT及二者联合诊断在单发骨转移病变定性诊断中的价值。方法 对102例全身骨显像表现为单发异常核素分布的恶性肿瘤患者行骨病变部位CT扫描。全身骨显像、CT及二者联合分别做出诊断,并与随访结果和病理对照。结果 102例患者,经随访和病理证实有53例为骨转移瘤。全身骨显像、CT与二者联合诊断骨转移瘤灵敏度分别为90.57％(48/53)、86.79％(46/53)、100%(53/53);特异度分别为61.22％(30/49)、97.96％(48/49)、91.84％(45/49);准确率分别为76.47％(78/102)、92.16％(94/102)、96.08％(98/102);阳性预测值分别为71.64%(48/67)、97.87%(46/47)、92.98%(53/57);阴性预测值分别为85.71%(30/35)、87.27%(48/55)、100%(45/45)。CT诊断特异度、准确率及阳性预测值优于全身骨显像(P＜0.05)。二者联合诊断特异度、准确率及阳性预测值明显优于单纯全身骨显像(P＜0.05),灵敏度和阴性预测值明显优于单纯CT(P＜0.05)。结论 CT有助于区分全身骨显像单发病变的良恶性。全身骨显像与CT联合诊断可明显提高肿瘤患者单发骨转移瘤的诊断准确率。
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| 关 键 词： | 肿瘤转移 放射性核素显像 体层摄影术 X线计算机 诊断显像 |
| 收稿时间： | 2010/7/27 0:00:00 |
| 修稿时间： | 2010/8/31 0:00:00 |
CT combined with radionuclide whole-body bone imaging in diagnosis of single bone metastasis |
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| WANG Jian-fang,ZHAO Xin-ming,ZHANG Jing-mian,WANG Ying-chen,ZHANG Zhao-qi,LI De-zhi,SUN Li and DAI Chun-nuan.CT combined with radionuclide whole-body bone imaging in diagnosis of single bone metastasis[J].Chinese Journal of Medical Imaging Technology,2011,27(3):594-598. |
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| Authors: | WANG Jian-fang ZHAO Xin-ming ZHANG Jing-mian WANG Ying-chen ZHANG Zhao-qi LI De-zhi SUN Li and DAI Chun-nuan |
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| Institution: | Department of Nuclear Medicine, Hebei Medical University Fourth Hospital,Shijiazhuang 050011, China;Department of Nuclear Medicine, Hebei Medical University Fourth Hospital,Shijiazhuang 050011, China;Department of Nuclear Medicine, Hebei Medical University Fourth Hospital,Shijiazhuang 050011, China;Department of Nuclear Medicine, Hebei Medical University Fourth Hospital,Shijiazhuang 050011, China;Department of Nuclear Medicine, Hebei Medical University Fourth Hospital,Shijiazhuang 050011, China;Department of Nuclear Medicine, Hebei Medical University Fourth Hospital,Shijiazhuang 050011, China;Department of Nuclear Medicine, Hebei Medical University Fourth Hospital,Shijiazhuang 050011, China;Department of Nuclear Medicine, Hebei Medical University Fourth Hospital,Shijiazhuang 050011, China |
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| Abstract: | Objective To observe the diagnosis value for solitary bone metastasis in patients with malignant tumor with bone scan,CT scan and combination analysis.Methods 99mTc-methylenebisphosphonate(MDP) bone scan was performed on patients with malignant tumor,102 patients with bone solitary lesion were selected and underwent CT scan immediately after bone scan.The final diagnosis was proved by clinical follow-up or pathology.Results Fifty-three patients in 102 cases were diagnosed bone metastases.The diagnostic sens... |
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| Keywords: | Neoplasm metastasis Radionuclide imaging Tomography X-ray computed Diagnostic imaging |
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