斑马鱼在发育儿科学领域的研究应用

斑马鱼作为新型模式动物的优势正在逐渐被人们所认识.由于斑马鱼易于饲养、发育快速、胚胎透明、繁殖力强等特点,尤其是和人类相似的基因结构和调节模式,以及各器官的发育及疾病的发生、发展与人类相应系统有许多共同特点,使其成为研究脊椎动物器官发育和人类疾病的重要模式动物.该文就斑马鱼在发育儿科学领域主要器官的应用概况作一综述.

Applications of the zebrafish in the studies of developmental pediatrics

Zebrafish as a new animal model is gradually being recognized. Easy fed, growing rapidly,transparent embryo, strong reproduction, especially similar with human in gene structure, body regulation patterns, and the development of organs and disease, all those characteristics make zebrafish significant in development of vertebrate animal and human disease. This review focuses on discussing the applications of the major organs of zebrafish in the studies of developmental pediatrics.