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炎症型心肌病研究进展
引用本文:孙妍. 炎症型心肌病研究进展[J]. 国际儿科学杂志, 2011, 38(2): 141-143. DOI: 10.3760/cma.j.issn.1673-4408.2011.02.015
作者姓名:孙妍
作者单位:山东大学附属省立医院儿科,济南,250021
摘    要:病毒性心肌炎可以引起严重的心肌损伤和急性心力衰竭,进而演变成扩张型心肌病,称为炎症型心肌病.免疫系统在病毒性心肌炎向扩张型心肌病的转化中起重要作用,包括病毒RNA持续复制、免疫介导损伤和细胞凋亡等细胞免疫反应,及抗心肌抗体等体液免疫应答.临床治疗方面,除抗心力衰竭、营养心肌之外,应进一步强调利巴韦林、免疫球蛋白、α1受...

关 键 词:炎症型心肌病  免疫  心肌炎

Progress in inflammatory cardiomyopathy
SUN Yan. Progress in inflammatory cardiomyopathy[J]. International Journal of Pediatrics, 2011, 38(2): 141-143. DOI: 10.3760/cma.j.issn.1673-4408.2011.02.015
Authors:SUN Yan
Abstract:Viral myocarditis can cause severe myocardial injury and even acute heart failure, then evolve into dilated cardiomyopathy, known as inflammatory cardiomyopathy. Immune reaction plays a key role in the transformation from viral myocarditis into dilated cardiomyopathy, including virus RNA continuous replication,immune-mediated injury, cellular apoptosis, other cellular immune response , myocardial antibodies and other humoral immune response. In the clinical treatment, besides anti-heart failure and cardiac nutrition, the use of ribavirin, α1-receptor blockers, β-receptor blockers, calcium channel blockers, angiotensin converting enzyme inhibitors and spironolactone should be emphasized.
Keywords:Inflammatory cardiomyopathy  Immune  Myocarditis
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