Hormonal profile of puberty in South Australian children II |
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| Authors: | J. L. PENFOLD T. J. C. BOULTON M. J. THOMSETT G. HARVEY S. E. CROMPTON A. VIMPANI M. A. PREECE |
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| Affiliation: | University of Adelaide Department of Paediatrics, The Adelaide Children's Hospital Inc., North Adelaide, South Australia. |
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| Abstract: | Serum follicle stimulating hormone (FSH), luteinising hormone (LH) and oestradiol (E2) concentrations in 117 girls aged 8 to 17.9 years were related to chronological age (CA), bone age (BA), breast development (B1–5+) and pubic hair development (PH1–5+). A progressive rise in serum LH and E2 was noted in relation to CA, BA and pubertal development. Serum FSH levels reached a peak in mid-puberty and fell thereafter. The FSH/LH ratio decreased with advancing CA and BA. In comparing the data in girls (Part II) with that in boys (Part I) serum FSH and LH levels began to rise earlier in girls and were generally higher than levels seen in boys throughout puberty. Similarly, an earlier rise in serum E2 in girls compared with T in boys supported the concept of an earlier activation of the female gonad. |
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