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不同炮制工艺对黄连中盐酸小檗碱含量的影响
引用本文:邹红,梅静,许腊英.不同炮制工艺对黄连中盐酸小檗碱含量的影响[J].湖北中医学院学报,2008,10(1):36-38.
作者姓名:邹红  梅静  许腊英
作者单位:[1]武汉市洪山区邮电科学研究院卫生服务中心,湖北武汉430074 [2]湖北中医学院药学院2005级硕士研究生,湖北武汉430065 [3]湖北中医学院药学院,湖北武汉430065
摘    要:目的对黄连的生品、酒制品、姜制品和吴茱萸制品中的盐酸小檗碱含量进行测定,为以后黄连炮制工艺提供依据。方法采用高效液相色谱法。流动相:乙腈∶水(磷酸盐溶液,磷酸调pH值,(28∶72v/v);测定波长:346nm;柱温:25℃;流速:1ml/min。结果炮制之后黄连中小檗碱的含量均有不同程度的提高,其增加程度分别为姜黄连〉酒黄连〉吴萸连〉生黄连。结论这三种炮制方法所炮制出来的黄连,其盐酸小檗碱的含量没有显著性差异。

关 键 词:黄连  炮制品  盐酸小檗碱  含量测定
文章编号:1008-987X(2008)01-0036-03
修稿时间:2007年7月10日

Effects of Different Processing Methods on Berberine Hydrochloride Content of Rhizoma Coptidis
Zhou Hong,Xu Laying,Mei Jing.Effects of Different Processing Methods on Berberine Hydrochloride Content of Rhizoma Coptidis[J].Journal of Hubei College of Traditional Chinese Medicine,2008,10(1):36-38.
Authors:Zhou Hong  Xu Laying  Mei Jing
Institution:Zhou Hong, Xu Laying, Mei Jing( 1. Health Service Center of Wuhan Research Institute of Posts and Communications, Wuhan, Hubei, 430074 ; 2. Postgraduate student of Pharmaceutical School of HCTCM, Wuhan, Hubei, 430065 ; 3. Pharmaceutical School of HCTCM, Wuhan, Hubei, 430065)
Abstract:Objective: Coptis, liquor products, ginger products and berberine hygiene goods are measured to provide evidence for the subsequent processing technology of coptis. Method: Using HPLC. The mobile phase: Acetonitrile: Water (Phosphate Solution, Phosphate-PH) (28: 72v/v); Determination wavelength: 346nm; Velocity; lml/min. Results: Berbcrine hygiene goods increase in various ways after the processing technology . The situation after increase is turmeric even 〉 Liqour Huanglian 〉 Wu Yu Lian 〉 Health Huanglian. Conclusions: The content of berberine hygiene goods in coptis has no significant difference by these three methods.
Keywords:coptis  processed products  berberine hygiene goods  determination
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