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Focal nodular hyperplasia-like lesion of the liver in a child previously treated for nephroblastoma
Authors:Takeyama Junji  Ando Ryo  Sato Tomoyuki  Nio Masaki  Shimanuki Yoshihisa  Sato Atsushi  Imaizumi Masue
Institution:Departments of Pathology,;Surgery,;Radiology and;Hematology and Oncology, Miyagi Children's Hospital, Sendai, Japan
Abstract:Described herein is the case of an 8-year-old boy who developed a hepatic nodular lesion after having received anti-neoplastic therapy for nephroblastoma. Histological examination of the excised specimen indicated a disordered arrangement of hepatic components with hemangioma-like features. This case was diagnosed as a variant of focal nodular hyperplasia. It is speculated that this hepatic lesion is a late complication of treatment for nephroblastoma and might develop from congenital malformative area of the liver.
Keywords:focal nodular hyperplasia  hamartoma  hepatic nodule  nephroblastoma  veno-occlusive disease
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