198株屎肠球菌的临床分布及耐药性分析

目的：了解医院屎肠球菌（EFM）的临床分布及耐药状况，为临床治疗与合理使用抗菌药物提供参考。方法将临床分离的屎肠球菌进行培养鉴定，采用纸片扩散法（K-B法）进行药物敏感试验。结果分离到198株屎肠球菌，主要来自于尿液、痰液和粪便标本，分别占50.0%、30.8%和7.6%，标本主要分离于重症监护病房（ICU）、泌尿外科和呼吸内科。屎肠球菌对多种抗菌药物耐药，对万古霉素、替考拉宁的耐药率较低，分别为1.0%和2.5%。屎肠球菌对利奈唑胺敏感率为100%。结论屎肠球菌可引起临床各类感染，且多耐药率高，治疗困难，应引起临床高度重视。

198 Strains of Excrement Enterococcus Clinical Distribution and Drug Resistance Analysis

Objective To understand the nosocomial Enterococcus faecium（EFM） clinical distribution and drug resistance,and provide reference for rational use of antibacterial drugs and clinical treat-ment. Methods The clinical isolates of Enterococcus faecium were cultured and identified, using disk diffusion method （K-B） for drug sensitivity test. Results 198 isolates of Enterococcus faeci-um, mainly from urine, sputum and stool samples, accounted for 50%,30.8% and 7.6%,were main-ly isolated from intensive care unit（ICU）, and Respiratory Department of Internal Medicine Depart-ment of urology. Antimicrobial resistance in Enterococcus faecium, resistance to vancomycin, te-icoplanin is a low rate, respectively 1% and 2.5%. Enterococcus faecium to linezolid sensitive rate is 100%.Conclusions Enterococcus faecium clinical types can cause infection, and the multi drug resistance rate high, difficult to treat, should arouse more attention in clinic.