急性下壁心肌梗死院外溶栓的治疗

目的　探讨急性下壁心肌梗死在院外早期静脉溶栓治疗对其生存率的影响及其临床意义。方法　选择呼叫120后在院外进行静脉溶栓的急性下壁心肌梗死患者100例为观察组, 80例未溶栓的急性下壁心肌梗死患者作为对照组, 并按发病至静脉溶栓开始的时间不同将观察组患者分为A组(30例), B组(34例), C组(36例)。观察溶栓后冠脉再通率、心功能、心律失常、低血压状态及院内病死率有无差异。结果　观察组(A、B、C3组) 患者之间在再通率(分别为76. 67%、52 .94%、38 .89% ) 及病死率方面比较差异有显著性意义(P<0 .05), 溶栓组与非溶栓组之间在再通率(分别为65. 00%、21 .25% ) 及病死率方面比较差异有显著性意义(P<0 .05)。结论　无禁忌证的急性下壁心肌梗死患者适宜院外静脉溶栓, 静脉溶栓的时间越早, 冠脉再通率及生存率越高。

The Clinical Observation of Thrombolysis Therapy in Pre-hospital on the Patients with Inferior Myocardial Infarction

Objective To assess the clinical benefici al of early thrombolysis therapy in pre-hospital on the patients with inferior m yocardial infarction and its effection for survival rate.Methods The study group consisted of 100 cases who call the emergency number-120 and utilize thrombolysis therapy in pre-hospital. The cont rol group consisted of 80 cases without giving thrombolysis therapy. The patient s were divided into three groups: A (30 cases), B (34 cases), C (36 cases) by th e time from fall ill to treatment. The difference was observed among coronary ar tery reperfusion rate, heart function, arrhythmia, low blood press state,in-hos pital mortality after thrombolysis therapy.Results There is significant difference on reperfusion rate and mortality between the three subgroups (P<0.05).There is significant difference on reperfusion rate and mortality between thrombolysis and control gr oup too (P<0.05).Conclusion (1)The earlier the throm bolysis therapy is used on the patients with inferior myocardial infarction, the higher the coronary artery reperfusion rate and survival rate are. (2) The acut e inferior myocardial infarction patients without controlled indication suitable thrombolysis therapy in pre-hospital.