Medical and Revascularization Management of Stable Ischemic Heart Disease: An Overview |
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| Authors: | Qais Radaideh Nicolas W. Shammas Ghassan E. Daher Rayan Jo Rachwan |
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| Affiliation: | 1.Midwest Cardiovascular Research Foundation, Davenport, Iowa;2.University of Iowa Hospitals and Clinics, Iowa City;3.SSM Health Saint Louis University Hospital, St. Louis, Missouri;4.Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin |
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| Abstract: | Stable ischemic heart disease (SIHD) affects approximately 10 million Americans with 500,000 new cases diagnosed each year. Patients with SIHD are primarily managed in the outpatient setting with aggressive cardiovascular risk factor modification via medical therapy and lifestyle changes. Currently, this approach is considered as the mainstay of treatment. The recently published ISCHEMIA trial has established the noninferiority of medical therapy in comparison to coronary revascularization in patients with moderate to severe ischemia. Percutaneous coronary intervention is currently recommended for patients with significant left main disease, large ischemic myocardial burden, and patients with severe refractory angina despite maximal medical therapy. |
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| Keywords: | stable ischemic heart disease functional flow reserve medical therapy primary outcome intravascular ultrasound revascularization |
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