24小时食管pH监测对胃食管反流病的诊断意义研究

目的探讨24h食管pH值与胃食管反流之间的关系，为临床诊治胃食管反流病提供科学依据。方法用CTD-svnectics公司便携式动态pH监测仪，对52例有胃食管反流症状者进行24h食管pH监测。采用Johson和DeMeester6种参数指标．对患者进行综合评分以反映病人的反流程度。结果监测病例组6种参数指标均显著高于对照组（P〈0．01）；DeMeester评分〉14．72．总阳性率为57．7％；以pH〈4的反流次数诊断阳性率最高（57．7％），卧位pH〈4的总时间诊断阳性率最低（15．4％）。结论24h食管pH监测给反流性疾病的诊断和药物治疗提供了依据，提高了对胃食管反流疾病的认识和治疗效果。

Investigation of Clinical Characteristics of 24-hour Esophageal pH Monitoring in Gastroesophageal Reflux Disease

OBJECTIVE To discuss the relation between value of 24-hour esophageal pH monitoring and gastroesophageal reflux, and further more provide scientific basis for the clinic diagnosis and treatment of GERD. METHODS CTD-synecties dynamic pH instrument and computer procedure software were used to monitor and analyze 24h pH esophagus value of the 52 eases. Johson and DeMeester's 6 parameters were adopted to evaluate the patients' reflux degree. RESULTS The parameters were respectively between the two groups (P<0.01). The total positive rate of DeMeester score over 14.72 was 57.7%.The total time percentage of pH<4 and the positive diagnosis rate of reflux times were the highest (57.7%). The positive diagnosis rate of total time in under the lying position pH<4 condition was the lowest(15.4%). CONCLUSION 24h pH Dynamic Monitoring is proved to be an objective and effective means of GERD diagnoses and treatment.