Nerve transfer helps repair brachial plexus injury by increasing cerebral cortical plasticity |
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| Authors: | Guixin Sun, Zuopei Wu, Xinhong Wang, Xiaoxiao Tan, Yudong Gu |
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| Affiliation: | [1]Department of Trauma Surgery, East Hospital, Tongji University School of Medicine, Shanghai, China; [2]Department of Physiology & Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China; [3]Medical School of the University of Queensland, Brisbane, St. Lucia, Queensland, Austualia; [4]Department of Hand Surgery, Huashan Hospital, Fudan University, Shanghai, China |
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| Abstract: | In the treatment of brachial plexus injury, nerves that are functionally less important are transferred onto the distal ends of damaged crucial nerves to help recover neuromuscular function in the target region. For example, intercostal nerves are transferred onto axillary nerves, and accessory nerves are transferred onto suprascapular nerves, the phrenic nerve is transferred onto the musculocutaneous nerves, and the contralateral C7 nerve is transferred onto the median or radial nerves. Nerve transfer has become a major method for reconstructing the brachial plexus after avulsion injury. Many experiments have shown that nerve transfers for treatment of brachial plexus injury can help reconstruct cerebral cortical function and increase cortical plasticity. In this review article, we summarize the recent progress in the use of diverse nerve transfer methods for the repair of brachial plexus injury, and we discuss the impact of nerve transfer on cerebral cortical plasticity after brachial plexus injury. |
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| Keywords: | nerve regeneration brachial plexus injury nerve transfer cortical plasticity intercostal nerve phrenic nerve radial nerve cerebral functional reconstruction review neural regeneration |
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