超声造影在判断脑胶质瘤手术肿瘤残留中的应用价值

目的探讨超声造影在判断脑胶质瘤手术肿瘤残留中的应用价值。方法 31例胶质瘤患者,于术中瘤体摘除前后行常规超声和超声造影检查,对照术前肿瘤回声及超声造影特点观察术后手术残腔以判断肿瘤残余情况。结果以病理结果为金标准,常规手术与超声造影引导下手术肿瘤全切除率分别为45.16%和74.19%(P0.05)。超声造影判断残余肿瘤的敏感性为85.71%,特异性为90.32%;常规超声判断残余肿瘤的敏感性为61.91%,特异性为83.87%。超声造影判断肿瘤残留病理符合率与常规超声差异无统计学意义(P0.05)。结论超声造影在胶质瘤手术肿瘤残留判断中具有较好的临床辅助价值。

Appfication value of contrast-enhanced ultrasonography in judging tumor residues after brain glioma operation

Objective To explore application value of contrast-enhanced ultrasonography in judging tumor residues after brain glioma operation. Methods Thirty-one patients with brain glioma were examined by conventional uhrasonography and contrast-enhanced ultrasonography before and after removal of tumor. Compared with preoperative tumor echo and imaging characteristics, tumor residual cavities after operation were observed to judge residual tumor. Results The tumor resection rates of routine operation and contrast-enhanced ultrasound guided operation were 45.16% and 74.19%, respectively, in which the latter was higher than the former （P〈0.05） according to pathologic result. The sensitivity of judging residual tumor using contrast- enhanced uhrasonography was 85.71% and the specificity was 90.32%. However, the sensitivity of conventional ultrasonography was 61.91% and the specificity was 83.87%. There was significant difference in pathology coincidence rate of residual tumor between contrast-enhanced ultrasonography and conventional uhrasonography（P〈0.05）. Conclusion Contrast-enhanced ultrasonography has important clinical value in judging tumor residues after brain glioma operation.