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文拉法新治疗不稳定型心绞痛伴抑郁症的疗效观察
引用本文:冯军,张敏,刘文博.文拉法新治疗不稳定型心绞痛伴抑郁症的疗效观察[J].医学理论与实践,2005,18(4):380-381.
作者姓名:冯军  张敏  刘文博
作者单位:辽宁省葫芦岛市化工医院心内科,125001
摘    要:目的:观察文拉法新对不稳定型心绞痛伴抑郁症的疗效。方法:1 3 4例患者随机分成两组,在常规治疗基础上治疗组每日加用文拉法新5 0~1 5 0mg口服,均观察6周。结果:在治疗不稳定型心绞痛基础上,加用文拉法新能有效清除或改善抑郁症状。文拉法新对提高心绞痛缓解率不明显,心血管事件的发生率尚无肯定的疗效。结论:文拉法新不良反应少,能有效地清除或改善抑郁症状,提高患者的生活质量,但也不能忽视病人的心理治疗和心理护理

关 键 词:心绞痛  不稳定型  文拉法新  抑郁症
文章编号:1001-7585(2005)04-0380-02
修稿时间:2004年11月11

The Observation on the Curative Effect of Venlafaxine for Unstable Angina Pectoris with Depression
FENG Jun,ZHANG Min,LIU Wenbo.The Observation on the Curative Effect of Venlafaxine for Unstable Angina Pectoris with Depression[J].The Journal of Medical Theory and Practice,2005,18(4):380-381.
Authors:FENG Jun  ZHANG Min  LIU Wenbo
Institution:FENG Jun,ZHANG Min,LIU Wenbo. Heart Internal Medicine Department,Huagong Hospital of Huludao City,Liaoning Province 125001
Abstract:Objective:To observe the curative effect of venlafaxine in the treatment of unstable angina pectoris with depression.Methods: 134 patients were divided into two groups randomly. The control group received routine treatment. On the basis of it, the treatment group was treated by additionally taking vanlafaxine orally 50~150mg a day. Both groups were observed for six weeks. Results: Vanlafaxine did not show significant effect on releasing the angina pectoris. Besides, there was no definite effect on exhibiting the occurrence of the cardiovascular incidents.Conclusion: Venlafaxine has little harmful effects. It can effectively eliminate or improve the symptom of the depression,and improve the patients' life quality. However, psychotherapy and psychological nursing should also be taken into full consideration.
Keywords:Angina pectoris  Unstable type  Venlafaxine  Depression
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