不同消化道重建方式对胃癌合并2型糖尿病患者血糖的影响 |
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引用本文: | 张天辉,;戴璟瑜.不同消化道重建方式对胃癌合并2型糖尿病患者血糖的影响[J].中国现代手术学杂志,2014(6):409-412. |
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作者姓名: | 张天辉 ;戴璟瑜 |
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作者单位: | [1]深圳市龙岗区坪地人民医院外科,广东深圳518000; [2]深圳市龙岗区中心医院普外科,广东深圳518000 |
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摘 要: | 目的探讨胃癌合并2型糖尿病患者行不同消化道重建手术方式对血糖的影响。方法回顾性分析我院2010年1月~2012年12月收治的53例远端胃癌合并2型糖尿病患者的临床资料,根据消化道重建方式分为两组:Ⅰ组25例,采用BillrothⅠ式手术行消化道重建;Ⅱ组28例,采用BillrothⅡ式手术行消化道重建。比较两组术后血糖的变化及疗效。结果Ⅰ组术后空腹血糖(FBG)、OGTT 2h血糖(2h PBG)、糖化血红蛋白(Hb A1c)及空腹C肽与术前比较均无明显变化(均P0.05),Ⅱ组术后FBG、2h PBG及Hb A1c较术前明显降低(均P0.05),空腹C肽较术前明显升高(P0.05)。两组患者术后FBG、2h PBG、Hb A1c及空腹C肽等指标比较均具有统计学差异(均P0.05)。Ⅰ组临床有效率为20%,Ⅱ组为92.9%,组间比较差异具有统计学意义(χ2=28.876,P0.01)。结论 BillrothⅡ式消化道重建方式对于胃癌合并2型糖尿病患者具有一定的血糖控制作用。
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关 键 词: | 糖尿病 2型 胃肿瘤 Billroth手术 |
The Effect on Blood Glucose of Different Gastrointestinal Reconstruction after Radical Surgery for Gas- tric Cancer Patients with Type-2 Diabetes MelHtus |
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Institution: | ZHANG Tian-hui DAI Jing-yu ( 1. Department of Surgery, Pingdi People 's Hospital of Longgang District, Shenzhen 518000, Guangdong , China; 2. Department of General Surgery, Central Hospital of Longgang District, Shenzhen 518000, Guangdong , China) |
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Abstract: | Objective To explore the effect on blood glucose of different alimentary reconstruction after radical surgery for gastric cancer patients with type-2 diabetes mellitus (T2DM). Methods The clinical data of 53 gastric cancer patients with T2DM admitted from January 2010 to December 2012 were analyzed retrospec- tively. They were divided into two groups according to different types of alimentary reconstruction: group Ⅰ were performed BillrothⅠ (n = 25, ), and group Ⅱ were carried out Billroth Ⅱ (n = 28). Results There was no statistical difference in FBG, 2h PBG, HbAle and peptide C before and 6 months after surgery in group Ⅰ (P 〉0.05). The FBG, 2h PBG and HbAle were decreased, and the peptide C was increased 6 months af- ter operation than those before the operation in group Ⅱ ( P 〈 0.05 ). There were statistic differences in all the laboratory indexes between two groups after the surgery ( P 〈 0.05 ). The clinical effective rate was 20% in group Ⅰ and 92.9% in group Ⅱ, and there was statistic difference between two groups (X2 = 28. 876, P 〈 0.01 ). Conclusion The reconstructive surgery of Billroth Ⅱ anastomosis is an effective control method of blood glu- cose for gastric cancer patients with T2DM. |
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Keywords: | diabetes mellitus type-2 stomach neoplasms Billroth's operation |
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