| 急性少量饮酒对P300参数的影响 |
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| 引用本文： | 张玺,邢丽冬,钱志余,李宁,何俊豪,邓建辉,于婷婷. 急性少量饮酒对P300参数的影响[J]. 生物医学工程研究, 2014, 0(4): 231-235 |
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| 作者姓名： | 张玺 邢丽冬 钱志余 李宁 何俊豪 邓建辉 于婷婷 |
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| 作者单位： | 南京航空航天大学自动化学院,南京210016 |
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| 基金项目： | 国家自然科学基金资助项目（61171059）;国家自然科学基金资助项目（61075107）; 科技部十二五国家科技支撑计划课题（2012BAI23B07）; 中央高校基本科研业务费专项基金资助项目（NZ2014307） |
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| 摘 要： | 为研究急性少量饮酒对认知功能的影响,对22名志愿者采集轻度饮酒前以及饮酒后两小时的脑电信号,利用事件相关电位技术提取P300电位,以P300峰值与潜伏期为指标对其进行研究。实验结果表明,志愿者饮酒后0.5 h到1.5 h内,P300峰值显著提高,其他时段无显著性差异,P300潜伏期各时段间均无显著差异。结合实验结果与神经行为认知状态测试(NCSE)得出结论,急性少量饮酒在短时间会提高大脑兴奋性,增强认知能力。
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| 关 键 词： | 事件相关电位 P300 潜伏期 急性少量饮酒 认知功能 |
Acute Effect of Low Doses of Alcohol on P300 |
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| ZHANG Xi,XING Lidong,QIAN Zhiyu,LI Ning,HE Junhao,DENG Jianhui,YU Tingting. Acute Effect of Low Doses of Alcohol on P300[J]. Journal Of Blomedical Englneerlng Research, 2014, 0(4): 231-235 |
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| Authors: | ZHANG Xi XING Lidong QIAN Zhiyu LI Ning HE Junhao DENG Jianhui YU Tingting |
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| Affiliation: | ( College of Automation, Nanjing University of Aeronautics ＆ Astronautics, Nanjing 210016, China) |
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| Abstract: | Inorder to explore acute effect of low doses of alcohol,22 volunteers participated in this P300 ERP（ event related potential,ERP） experiment. We collected their EEG without drinking alcohol and 2 h after they drunk. The result showed that the P300 amplitudes collected at 0. 5 to 1. 5 h after drinking were higher than that collected without drinking. There was no difference in latency. It can be concluded that low doses of acute drinking alcohol can make cerebral excitarory,and enhance the cognitive ability. |
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| Keywords: | Event related potential P300 Latency Low doses of acute drinking alcohol Cognitive ability. |
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