基于脉搏波传导时间的连续血压监测系统

为了实现无创连续血压测量,提出了一种基于脉搏波传导时间(pulse transit time,PTT)的连续血压测量方案。通过同步采集心电(electrocardiogram,ECG)信号与光电脉搏波(photoplethysmograph,PPG)信号,以ECG的R波峰值点作为PTT的开始点,PPG信号的最大值点作为PTT的结束点,得到PTT,与水银血压计测得舒张压(diastolic blood pressure,DBP)与收缩压(systolic blood pressure,SBP)进行回归分析,得到了DBP和SBP的数学模型。利用该方法对41名身体健康的青年人进行实验,利用本方案得到的SBP与水银血压计的相关系数为0.82,其差值的平均数与标准偏差为0.15±2.05 mm Hg;得到的DBP与水银血压计的相关系数为0.73,其差值的平均数与标准偏差为0.12±2.16 mm Hg。利用Bland-Altman差值法对本系统血压测量方法与水银血压计测血压方法进行一致性检验,结果显示两种血压测量方法具有很好的一致性。

Continuous Blood Pressure Measurement based on Pulse Transit Time

To achieve continuous non-invasive blood pressure measurement,a method based on pulse transit time（ PTT） was presented. We got PTT from electrocardiograph（ ECG） and photoplethysmograph（ PPG）. The start point of PTT on ECG-R wave point and the stop point of PTT on PPG characteristic point was gotten. The mathematical model of systolic blood pressure（ SBP） and diastolic blood pressure（ DBP） were gotten by making regression analysis between PTT and SBP or DBP measured with a mercury sphygmomanometer. Forty-one healthy young people were studied using this method. The correlation coefficients of SBP and DBP between our system and the mercury sphygmomanometer were 0. 82 and 0. 73,respectively. It was found that the estimated SBP and DBP differed from the reference BP by 0. 15 ± 2. 05 mm Hg and 0. 12 ± 2. 16 mm Hg,respectively. The Bland-Altman method was used to check the consistency of the blood pressure measured by our system and the mercury sphygmomanometer. The results show that blood pressure measured by this method is good agreed with which measured by mercury sphygmomanometer.