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Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) Inhibitors |
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| Authors: | Ke Zheng Chul Min Park Sarah Iqbal Pamela Hernandez HaJeung Park Philip V LoGrasso Yangbo Feng | |
| Institution: | †Medicinal Chemistry, ‡Discovery Biology, §Crystallography/Modeling Core Facility, Translational Research Institute, and ∥Department of Molecular Therapeutics, The Scripps Research Institute, 130 Scripps Way, #2A1, Jupiter, Florida 33458, United States | |
| Abstract: | ||
| Keywords: | JNK3 kinase inhibitor Parkinson’ s disease (PD) pyridopyrimidinone mitochondrial dysfunction | |