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Double blind exploratory study on de novo lipogenesis in preterm infants on parenteral nutrition with a lipid emulsion containing 10% fish oil
Affiliation:1. Division of Neonatology, Polytechnic University of Marche, Salesi Children''s Hospital, Via Corridoni 11, 60123 Ancona, Italy;2. Pediatric Research Institute “Città della Speranza”, C.so Stati Uniti 4, 35127 Padova, Italy;3. Cardiac Anaesthesia/Intensive Care Unit, Bambino Gesù Children''s Hospital, Piazza Sant''Onofrio 4, 00165 Roma, Italy;1. Div of Pediatrics, Dept of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden;2. Karolinska Institutet, Department of Clinical Sciences, Danderyds Hospital & Department of Surgery, Ersta Hospital, Stockholm, Sweden;3. Pediatric Endocrinology Unit, Dept. of Woman and Child Health, Karolinska Institute and Hospital, Stockholm, Sweden;4. Department of Surgery, Orebro University Hospital, Orebro, Sweden;5. Dept. of Molecular Endocrinology, Karolinska Institute and Hospital, Stockholm, Sweden;1. Obstetrical, Perinatal, and Pediatric Epidemiology Team, Epidemiology and Biostatistics Sorbonne Paris Cité Research Center (U1153), INSERM, Paris, France;2. APHP, Neonatology Unit, Necker Hospital, Paris, France;3. Rouen University Hospital, Neonatal Medicine, Rouen; Institute of Biomedical Research, University, Inserm Avenir Research Group, IFR 23, Rouen, France;4. Department of Neonatology, Human Nutrition Research Center, Hospital E. Herriot, Lyon, France;5. APHP, Neonatology Unit, Trousseau Hospital, Paris, France;6. Clinical Epidemiology and Biostatistics Department, CHRU Nancy, Nancy, France;7. Paul Sabatier University, Toulouse, France;8. Department of Neonatology, CHU Nantes, Nantes, France;9. Montpellier University Hospital Center, Neonatal and Pediatric Intensive Care Unit, Montpellier, France
Abstract:
Keywords:Lipids  Isotope labeling  Lipogenesis  Premature infants  Omega-3 fatty acids  Omega-6 fatty acids  ASR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0045"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  absolute synthesis rate  CE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0055"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  cholesterol esters  C16-CE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0065"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  cholesterol esters palmitate  C16-PL"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0075"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  phospholipids palmitate  C16-TG"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0085"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  triglycerides palmitate  C18-CE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0095"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  cholesterol esters stearate  C18-PL"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0105"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  phospholipids stearate  C18-TG"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0115"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  triglycerides stearate  C18:1ω9-CE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0125"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  cholesterol esters oleate  C18:1ω9-PL"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0135"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  phospholipids oleate  C18:1ω9-TG"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0145"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  triglycerides oleate  DHA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0155"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  docosahexaenoic acid  EPA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0165"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  eicosapentaenoic acid  FA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0175"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  fatty acid  FC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0185"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  free cholesterol  FO"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0195"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  fish oil  FSR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0205"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  fractional synthesis rate  GC–MS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0215"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  gas chromatography–mass spectrometry  GC-IRMS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0225"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  gas chromatography/isotope-ratio mass spectrometry  IV"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0235"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  intravenous  LCP"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0245"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  long chain polyunsaturated fatty acids  LE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0255"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  lipid emulsion  MCT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0265"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  medium chain triglycerides  PI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0275"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  preterm infant  PL"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0285"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  phospholipids  PN"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0295"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  parenteral nutrition  PNALD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0305"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  parenteral nutrition-associated liver disease  RCT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0315"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  randomized controlled trials  SO"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0325"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  soybean oil  SREBP-2"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0335"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  sterol regulating element binding protein-2  TG"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0345"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  triglycerides
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