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Mammographically Occult Asymptomatic Radial Scars/Complex Sclerosing Lesions at Ultrasonography-Guided Core Needle Biopsy: Follow-Up Can Be Recommended
Institution:1. Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea;2. Department of Nursing, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea;3. Department of Biostatistics, Samsung Biomedical Research Institute, Seoul, Korea;4. Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea;5. Department of Radiation Oncology, Robert Wood Johnson Medical School, Cancer Institute of New Jersey, New Brunswick, NJ, USA;1. Division of Pediatric Urology, Department of Urology, University of Texas Southwestern Medical Center and Children’s Medical Center, Dallas, Texas;2. Texas Children’s Hospital-Baylor College of Medicine, Houston, Texas;3. Department of Urology, Children’s Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania;1. MTA-SE NAP B Peripheral Nervous System Research Group, Department of Neurology, Semmelweis University, Budapest, Hungary;2. Neurologische Praxis, Dr. Friedrich Behse/Dr. Josef Böhm, Berlin, Germany;3. Department of Neurology, Städtisches Klinikum Dessau, Dessau-Rosslau, Germany;1. Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, Minnesota, USA;2. Department of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Abstract:An increasing number of radial scars are detected by ultrasound (US), but their management is controversial. This study investigated the upgrade rate in mammographically occult radial scars/complex sclerosing lesions without epithelial atypia at US-guided 14-gauge core needle biopsy in asymptomatic patients. Nineteen mammographically occult benign radial scars/complex sclerosing lesions (median size, 7 mm; range, 3–23 mm) were included. Patients underwent surgical excision (n = 10) or vacuum-assisted excision, with follow-up US at least 6 mo after benign vacuum-assisted excision results (n = 8), or underwent US follow-up for 2 y after core needle biopsy (n = 1). Any cases with change in diagnosis to high-risk lesions or malignancy at excision were considered upgrades. The upgrade rate was 0.0%. Based on US findings, 15.8% (3/19) were Breast Imaging Reporting and Data System (BI-RADS) category 3, 68.4% (13/19) were BI-RADS category 4a and 15.8% (3/19) were BI-RADS category 4b. Follow-up with US can be considered for mammographically occult benign radial scar/complex sclerosing lesions diagnosed by US core needle biopsy in asymptomatic patients.
Keywords:Radial scar  Complex sclerosing lesion  Ultrasonography  Core needle biopsy
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