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Anti-tumor necrosis factor alpha monoclonal antibody (infliximab) for the treatment of Pyoderma gangrenosum associated with Crohn's disease
Authors:Zaccagna Alessandro  Bertone Alberto  Puiatti Paolo  Picciotto Franco  Sprujevnik Tatiana  Santucci Renato  Rossini Francesco Paolo
Affiliation:Institute for Cancer Research and Treatment (IRCC), Operative Unit of Dermatologic Surgery, Str.Prov.142, Km 3.95, 10060 Candiolo, Italy.
Abstract:Here we report a case of Pyoderma gangrenosum (PG) associated with Crohn's disease successfully treated with infliximab. The efficacy of this drug in many inflammatory diseases has already been reported, but its use in PG has only been seen in very few cases. Our study confirms that this therapy is a valid alternative solution for treating PG, which is often unresponsive to conventional therapies.
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