兔下颌骨骨膜牵张成骨的实验研究

目的 探讨骨膜牵张成骨术的新方法。方法 将自制骨膜牵张器固定于3只兔的双侧下颌骨表面，左侧行骨膜牵张，右侧不牵张，作为对照。牵张过程结束后处死所有动物，标本进行X线和组织学检查。结果 3只动物术后情况良好，无明显并发症。在大体标本和X线片上表现出新骨形成。组织学检查显示牵张区有成骨样细胞浸润和骨组织形成。结论 骨膜牵张成骨技术能够为骨缺损的修复提供一种新的方法。

Experimental Study of Mandibular Periosteal Distraction in Rabbits

Objective To investigate a novel technique for new bone formation-periosteal distraction osteogenesis. Methods A custom made periosteal distraction device was fixed to bilateral surface of the mandible in three rabbits. Periosteal distraction was performed on the left side of the mandible, the right side of the mandible served as the control. The animals were sacrificed at the end of distraction process. All the specimens were X-rayed and histologically examinated. Results All three animals survived with no obvious complications. Both in mass specimens and X-rays, there showed new bone formation on the distracted side of the mandible. In histological examinations, there was osteoblast-like cell infiltration and bone tissue formation in the distracted area. Conclusion Periosteal distraction osteogenesis can provide a novel technique for the repair of bone defects.