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| 鼠大脑中动脉安全间断阻断时间的实验研究 | |
| 引用本文： | 江涛,戴钦舜,刘恩重,赵立富,李昌盛. 鼠大脑中动脉安全间断阻断时间的实验研究[J]. 中国微侵袭神经外科杂志, 1998, 0(2) |
| 作者姓名： | 江涛 戴钦舜 刘恩重 赵立富 李昌盛 |
| 作者单位： | 哈尔滨医科大学第一附属医院神经外科，哈尔滨医科大学神经外科研究所，哈尔滨医科大学神经外科研究所，哈尔滨医科大学神经外科研究所，哈尔滨医科大学神经外科研究所 博士生 北京市神经外科研究所 北京 100050，哈尔滨 150010，哈尔滨 150010，哈尔滨 150010，哈尔滨 150010 |
| 摘 要： | 目的:载瘤动脉间断阻断是一种新型的辅助技术,在颅内动脉瘤夹闭术中有着相当大的实用性。方法:通过建立大鼠可复流的脑缺血—再灌注病理模型,探讨了间断阻断大脑中动脉安全阻断时间,间断阻断10min,复流5min。结果:在1h内不会造成明显的缺血性损伤和病理学体征。结论:此种方法如能与其它脑保护措施联合应用,将能发挥更大作用。 |
| 关 键 词： | 安全阻断时间 脑保护 动脉瘤 |
Experimental study of the safe time limite of intermittent middle cerebral artery occlusion in rats |
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| Jiang Tao,Dai Qinshun,Liu Enzhong et al Beijing Neurosurgical Institute. Experimental study of the safe time limite of intermittent middle cerebral artery occlusion in rats[J]. Chinese Journal of Minimally Invasive Neurosurgery, 1998, 0(2) | |
| Authors: | Jiang Tao Dai Qinshun Liu Enzhong et al Beijing Neurosurgical Institute |
| Affiliation: | Jiang Tao,Dai Qinshun*,Liu Enzhong* et al Beijing Neurosurgical Institute |
| Abstract: | To test the safe time limite of intermittent middle cerebral artery occlusion. Method: Intermittent MCA occlusion was studied by using a reflow permissible cerebral is-chemic reperf usion model in rat. Result: This experiment showed that 60 minutes intermittent occlusion with 5 minutes reperfusion after each 10 minutes ischemic period was well tolerated without obvious ischemic neurological deficits. Conclusion: The middle cerebral artery of rats can tolerate safely for 60 minutes intermittent occlusion. If neuroprotective procedure were used, the results mav even be better. |
| Keywords: | safe occlusive time cerebral pro- tection aneurysm |
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