肝脏局灶性结节性增生的诊断和处理

为了探讨对肝脏局灶性结节性增生诊治的合理方案，回顾性研究１９８４年～１９９８年经手术切除且经病理证实的６例肝局灶性结节性增生，并结合近期文献报道进行分析和探讨。６例肝局灶性结节性增生病人均无类固醇激素应用史，其中３例有临床症状，术前均未明确诊断而行手术切除，无手术死亡及术后并发症。肝局灶性结节性增生的准确诊断十分困难，但合理地联合应用多种影像学检查手段，可以提高诊断水平，对于无症状的确诊病例，可以采取密切随访及保守疗法；对于有症状的或生长迅速的或诊断不明确的病例应行外科手术切除

Diagnosis and Management of Liver Focal Nodular Hyperplasia

In order to explore and investigate the clinicopathological characters and reasonable diagnostic and therapeutic strategy of liver focal nodular hyperplasia(FNH),6 cases of FNH who admitted to our department and underwent surgery between 1984 and 1998 were retrospectively analyzed.All of them were confirmed by pathology.Also the recent literatures were reviewed.None of 6 cases had a history of using steroid hormone.3 cases presented with clinical symptoms.The preoperative diagnosis were equivocal.All of 6 cases received surgery,and the postoperative morbidity and mortality were zero.The article concluded that the diagnosis of FNH is very difficult,but the combination of several imaging modalities is preferred.For asymptomatic patients with an unequivocal diagnosis of FNH,observation should be recommended.Patients with tumor related symptoms,or a significant increase in tumor size during observation or in case of equivocal diagnosis,surgery should be performed.