原发性肝癌肝内转移途径的探讨

目的：探讨门脉逆流与肝癌肝内转移的关系。方法：应用彩色多普勒超声检测肝炎肝且、非肝炎肝癌组、肝炎组与对照组的门静脉－肝动脉瘘、门静脉逆流的发生率。结果肝炎肝癌组、肝炎组门静脉逆流的发生率均高于非肝炎肝癌组（P＜0．05，P＜0．01），且肝炎肝癌组最高（P＜0．05，P＜0．01，P＜0．001）；肝炎肝癌组肝内转移发生率明显高于非肝炎肝癌组（P＜0．01）；肝炎肝癌组与非肝炎肝癌组肿块内及周围的门静脉－肝脉瘘发生机率差异无显著性（P＞0．05）。结论门静脉逆流是引起肝癌肝内转移的主要途径。

Study of the route of intrahepatic metastasis of primary hepatic carcinoma

OBJECTIVE: To study the relationship between pylic countercurrent blood-flow and intrahepatic metastasis of hepatocarcinoma. METHODS: Portal vein-hepatic artery fistula and pylic countercurrent blood flow in the liver were examined by color Doppler ultrasound. Patients examined were divided into four groups: group 1, hepatocarcinoma with background of hepatitis, group 2, hepatocarcinoma without background of hepatitis, group 3, hepatitis and group 4, normal liver. RESULTS: Pylic countercurrent flood flow was most frequently observed in group 1 patients. Intrahepatic metastasis was more frequent in group 1 than in group 2 patients. There was no statistically significant difference in the frequency of portal vein-hepatic artery fistula formation around and inside of tumor between group 1 and group 2 patients. CONCLUSION: Intrahepatic metastasis of hepatocarcinoma is due to countercurrent blood flow in the portal system.