精神分裂症患者线段等分及数字等分研究

目的 评估精神分裂症患者忽视现象,探讨患者空间注意障碍及其与脑半球的关系.方法 采线段等分试验和数字等分试验对51例未用药精神分裂症患者进行评估,与55例正常对照者进行比较.结果 线段等分试验,患者组所有线段偏移率均为负值,其中平均偏移率(-0.02±0.03)%和线段2cm偏移率(-0.03±0.74)%与对照组[分别为(-0.00±0.01)%和(0.00±0.02)%]比较,差异有显著统计学意义(均P＜0.05);患者组的平均偏移率与零值比较,差异有显著性(P＜0.01);正常对照组的平均偏移率为负值,与零值比较差异有显著统计学意义(P＜0.05).数字等分试验,患者组偏移率均为负值,除间距3外,间距5(-0.07±0.18)%、7(-0.08±0.22)%和间距9(-0.09±0.28)%的偏移率均较对照组[分别为(-0.01±0.05)%、(0.01±0.08)%和(0.00±0.14)%]左偏,差异有显著性(均P＜0.05).结论 精神分裂症患者存在右偏忽视现象,提示患者空间注意受损,可能与左侧脑半球功能障碍有关.

Abstract：

Objective To investigate the existence of neglect and explore the relationship between spacial attentional deficits and hemisphere in patients with schizophrenia. Methods 51 schizophrenic patients and 55 healthy controls were measured with line bisection test and number bisection test、 Results In the Line Bisection Test,shcizophrenic patients group showed a negative deviation, in which the 2cm line( -0.03 ± 0. 74 )% and mean ( - 0. 02 ± 0. 03 ) % deviation rates were more significantly leftward than that of the normals ( ( 0. 00 ±0.02 ) %, ( - 0.00 ± - 0.01 ) %, P ＜ 0. 05 ) respectively. The mean deviation rates of the patients (P ＜ 0. 01 ) and control groups (P ＜ 0. 05 ) were also significantly leftward compared with zero value. In the number bisection test,schizophrenic patients group showed a negative deviation and a significant leftward bias on the interval 5 ( - 0.07 ±0.18)% ,7( -0.08 ±0.22)% and 9( -0.09 ±0.28)% ) than that of the normals(( -0.01 ±0.05)% ,(0.01± 0. 08 ) % and (0.00 ± 0.14 ) %, P ＜ 0.05 respectively). Conclusion Schizophrenic patients have a right-neglect, suggesting that spacial attentional deficits exist, and it may be related to the left cerebral hemisphere dysfunction.

A study of line bisection and number bisection in patients with schizophrenia

Objective To investigate the existence of neglect and explore the relationship between spacial attentional deficits and hemisphere in patients with schizophrenia. Methods 51 schizophrenic patients and 55 healthy controls were measured with line bisection test and number bisection test、 Results In the Line Bisection Test,shcizophrenic patients group showed a negative deviation, in which the 2cm line( -0.03 ± 0. 74 )% and mean ( - 0. 02 ± 0. 03 ) % deviation rates were more significantly leftward than that of the normals ( ( 0. 00 ±0.02 ) %, ( - 0.00 ± - 0.01 ) %, P ＜ 0. 05 ) respectively. The mean deviation rates of the patients (P ＜ 0. 01 ) and control groups (P ＜ 0. 05 ) were also significantly leftward compared with zero value. In the number bisection test,schizophrenic patients group showed a negative deviation and a significant leftward bias on the interval 5 ( - 0.07 ±0.18)% ,7( -0.08 ±0.22)% and 9( -0.09 ±0.28)% ) than that of the normals(( -0.01 ±0.05)% ,(0.01± 0. 08 ) % and (0.00 ± 0.14 ) %, P ＜ 0.05 respectively). Conclusion Schizophrenic patients have a right-neglect, suggesting that spacial attentional deficits exist, and it may be related to the left cerebral hemisphere dysfunction.