更昔洛韦联合西米替丁治疗婴幼儿轮状病毒肠炎疗效观察 |
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引用本文: | 杨康治 吴少华 陈正珊 项素素 冯思国. 更昔洛韦联合西米替丁治疗婴幼儿轮状病毒肠炎疗效观察[J]. 实用中西医结合临床, 2008, 8(1): 13-14 |
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作者姓名: | 杨康治 吴少华 陈正珊 项素素 冯思国 |
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作者单位: | 浙江省苍南县第二人民医院,苍南,325802 |
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摘 要: | 目的:探讨更昔洛韦联合西米替丁治疗婴幼儿轮状病毒肠炎的疗效。方法:将112例轮状病毒性肠炎患儿随机分为更昔洛韦组、更昔洛韦+西米替丁组和对照组三组。结果:治疗72h总有效率对照组、更昔洛韦组、更昔洛韦+西米替丁组分别为57.5%、87.5%、90.0%,更昔洛韦组、更昔洛韦+西米替丁组明显高于对照组(P<0.05或P<0.01);更昔洛韦+西米替丁组总有效率与更昔洛韦组比较差异无显著性意义(P>0.05),但显效率明显高于更昔洛韦组(P<0.05)。结论:更昔洛韦与西米替丁联合治疗婴幼儿轮状病毒肠炎疗效较好,值得临床应用。
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关 键 词: | 轮状病毒肠炎 更昔洛韦 西米替丁 婴幼儿 |
文章编号: | 1671-4040(2008)01-0013-02 |
收稿时间: | 2007-08-05 |
修稿时间: | 2007-08-05 |
The Effect of Ganciclovir and Cimetidine in Treatment of Infants Enteritis |
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Abstract: | Objective: To explore the effect of ganciclovir and cimetidine therapy on infants with rotavirus enteritis.Methods:112 infants with rotavirus enteritis were randomly divided into ganciclovir group, ganciclovir+cimetidine group and control group. Results: The total effective rates of control group, ganciclovir group and ganciclovir+cimetidine group in first 72 hours of the treatment were 57.5%, 87.5% and 90.0%. The total effective rates of ganciclovir group, ganciclovir+cimetidine group were significantly higher than that of control group(P 〈0.05&P 〈0.01).There was no significant difference between ganciclovir+cimetidine group and ganciclovir group(P 〉 0.05), but the notable effective rates of the former group were significantly higher than that of ganciclovir group (P 〈0.05).Conclusion: Ganciclovir and cimetidine in treating infants with rotavirus enteritis is effective. |
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Keywords: | Rotavirus enteritis Ganciclovir Cimetidine Infant |
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