首页 | 本学科首页   官方微博 | 高级检索  
     

不孕不育患者与抗精子抗体和抗子宫内膜抗体的相关性分析
引用本文:许晓清,吴方贵,邱耀芳. 不孕不育患者与抗精子抗体和抗子宫内膜抗体的相关性分析[J]. 中国热带医学, 2006, 6(8): 1371-1372
作者姓名:许晓清  吴方贵  邱耀芳
作者单位:深圳市罗湖区人民医院,广东,深圳,518001
摘    要:目的 探讨抗精子抗体(AsAb)和抗子宫内膜抗体(EMAb)检测在不育不孕症患者中的临床价值。方法应用酶联免疫吸附试验(ELISA法)对1197例不孕不育者进行了抗精子抗体与抗子宫内膜抗体检测,同时与健康组作对比研究。结果不孕不育组AsAb总阳性栓出率为21.7%(260/1197),男性病例阳性为18,4%(94/511),女性不孕病例检测阳性占24.2%(166/686);健康组AsAb阳性率则为3.6%(2/56),经统计学处理,P〈0.01。而686例女性不孕不育中原发组AsAb阳性占24.1%(60/249),继发不孕组占24.3%(106/437);EMAb检测不孕组为9,2%(63/686),原发不孕占7、6%(19/249),继发不孕占10.1%(44/437),健康孕妇组为0(0/28),两组对比P〈0.01。结论AsAb和EMAb与不孕(育)密切相关。

关 键 词:不孕不育 抗精子抗体 抗子宫内膜抗体
文章编号:1009-9727(2006)08-1371-02
收稿时间:2006-04-06
修稿时间:2006-04-06

Study on the correlation of infertility with antispermactic antibody and antiendometrial antibody
XU Xiao-qing,WU Fang-gui,QIU Yao-fang. Study on the correlation of infertility with antispermactic antibody and antiendometrial antibody[J]. China Tropical Medicine, 2006, 6(8): 1371-1372
Authors:XU Xiao-qing  WU Fang-gui  QIU Yao-fang
Affiliation:Luohu District Hospital of Shenzhen City, Shenzhen 518001, Guangdong, P. R. China
Abstract:Objective To explore the clinical value of antisperm antibody(AsAb) and antiendometrial antibody(EMAb) in diagnosis of infertility patients. Methods AsAb and EMAb of 1 197 infertility patients were determined by using ELISA and compared to those of normal controls. Results The total positive rate of AsAb in infertility group was 21.7%(260/1 197),the positive rate in male group was18.4%(94/511),24.2%(166/686) in female group and 3.6%(2/56) in normal control,showing significant difference(P<0.01).EMAb in female infertility group was 9.2%(63/686) ,the positive rates of AsAb and EMAb in primary infertility patients were 24.1%(60/249) and 7.6%(19/249) and the positive rates of AsAb and EMAb in secondary infertility were 24.3%(106/437) and 10.1%(44/437),while that in the control was 3.6%(1/28) and 0(0/28),showing significant difference(P<0.01). Conclusion AsAb and EMAb were closely associated with infertility.
Keywords:Infertility  Antisperm antibody(AsAb)  Antiendometrial antibody(EMAb)
本文献已被 CNKI 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号