| 正交试验优化复方南蛇藤胶囊水提取工艺 |
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| 引用本文： | 侯悦翰,林华庆,邓红,张蜀,余楚钦,林的仕. 正交试验优化复方南蛇藤胶囊水提取工艺[J]. 中国实验方剂学杂志, 2012, 18(2): 35-38 |
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| 作者姓名： | 侯悦翰 林华庆 邓红 张蜀 余楚钦 林的仕 |
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| 作者单位： | 广东药学院药物研究所,广东省药物新剂型重点实验室,广州 510006 |
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| 摘 要： | 目的:优选出复方南蛇藤胶囊的最佳水提工艺.方法:采用正交设计法,通过高效液相色谱法测定卫矛醇和原儿茶酸的含量为指标综合评价,优化提取工艺.结果:最佳水提工艺为加12倍量水,提取3次,每次2h.结论:优选的提取工艺稳定,可行.
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| 关 键 词： | 复方南蛇藤胶囊 正交设计 水提工艺 卫矛醇 原儿茶酸 |
| 收稿时间： | 2011-09-20 |
Water Extraction Technology of Compound Celastrus orbieulatus Capsule by Orthogonal Test |
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| HOU Yue-han,LIN Hua-qing,DENG Hong,ZHANG Shu,YU Chu-qin and LIN Di-shi. Water Extraction Technology of Compound Celastrus orbieulatus Capsule by Orthogonal Test[J]. China Journal of Experimental Traditional Medical Formulae, 2012, 18(2): 35-38 |
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| Authors: | HOU Yue-han LIN Hua-qing DENG Hong ZHANG Shu YU Chu-qin LIN Di-shi |
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| Affiliation: | Institute of Materia Medica, Guangdong Pharmaceutical University,Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangzhou 510006, China;Institute of Materia Medica, Guangdong Pharmaceutical University,Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangzhou 510006, China;Institute of Materia Medica, Guangdong Pharmaceutical University,Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangzhou 510006, China;Institute of Materia Medica, Guangdong Pharmaceutical University,Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangzhou 510006, China;Institute of Materia Medica, Guangdong Pharmaceutical University,Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangzhou 510006, China;Institute of Materia Medica, Guangdong Pharmaceutical University,Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangzhou 510006, China |
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| Abstract: | Objective: To optimize water extraction process of compound Celastrus orbieulatus capsule. Method: Extraction technology was optimized by orthogonal test with the content of dulcitol and protocatechuic acid determined by HPLC as index. Result: Optimum extraction technology was that extracted 3 times with 12 times the amount of water with 2 h each time. Conclusion: Optimized extraction process was scientific, stable and feasible. |
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| Keywords: | compound Celastrus orbieulatus capsule orthogonal test water extraction process dulcitol protocatechuic acid |
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