| 正交试验优选黄芪桂枝五物汤的水提取工艺 |
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| 引用本文： | 陈永祥,孙耀志,高松,郭水柱,陈洪英. 正交试验优选黄芪桂枝五物汤的水提取工艺[J]. 中国实验方剂学杂志, 2012, 18(2): 56-59 |
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| 作者姓名： | 陈永祥 孙耀志 高松 郭水柱 陈洪英 |
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| 作者单位： | 1. 河南中医学院药学院,郑州,450008
2. 河南宛西制药股份有限公司,河南南阳,473000 |
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| 摘 要： | 目的:优选黄芪桂枝五物汤的提取工艺.方法:用高效液相色谱法分别测定黄芪甲苷、芍药苷.以黄芪甲苷、芍药苷和干浸膏的含量为考察指标,通过正交试验法优选最佳提取工艺.结果:优选得到的工艺为药材加10倍水量浸泡0.5h、煎煮3次、每次煎煮1.5h.结论:最佳提取工艺稳定可行,可作为黄芪桂枝五物汤的提取工艺.
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| 关 键 词： | 黄芪桂枝五物汤 正交试验 提取工艺 |
| 收稿时间： | 2011-08-16 |
Optimization of Extraction Process of Huangqi Guizhi Wuwutang by Orthogonal Design |
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| CHEN Yong-xiang,SUN Yao-zhi,GAO Song,GUO Shui-zhu and CHEN Hong-ying. Optimization of Extraction Process of Huangqi Guizhi Wuwutang by Orthogonal Design[J]. China Journal of Experimental Traditional Medical Formulae, 2012, 18(2): 56-59 |
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| Authors: | CHEN Yong-xiang SUN Yao-zhi GAO Song GUO Shui-zhu CHEN Hong-ying |
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| Affiliation: | School of Pharmacy, Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China;Henan Wanxi Pharmaceutical Co. Ltd., Nanyang 473000, China;Henan Wanxi Pharmaceutical Co. Ltd., Nanyang 473000, China;Henan Wanxi Pharmaceutical Co. Ltd., Nanyang 473000, China;Henan Wanxi Pharmaceutical Co. Ltd., Nanyang 473000, China |
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| Abstract: | Objective: To optimize the extraction technology of Huangqi Guizhi Wuwutang. Method: The content of astragaloside and paeoniflori were determined by HPLC. The optimum extraction condition was investigated by orthogonal design; the content of astragaloside, paeoniflorin and the ratio of dry extraction were regarded as the detection index. Result: The optimum extraction was as follows: soaking in ten times amount of water for half an hour, extracting three times, every time for one and a half hour. Conclusion: The optimum technology was stable and feasible for the extraction of Huangqi Guizhi Wuwutang. |
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| Keywords: | Huangqi Guizhi Wuwutang orthogonal design extraction technology |
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