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| 响应面分析法优化葛根中异黄酮提取工艺 | |
| 引用本文： | 王艳艳,王团结,丁琳琳.响应面分析法优化葛根中异黄酮提取工艺[J].中国实验方剂学杂志,2012,18(2):45-48. |
| 作者姓名： | 王艳艳 王团结 丁琳琳 |
| 作者单位： | 1. 江苏联合职业技术学院连云港中医药分院,江苏连云港,222006 2. 江苏康缘药业股份有限公司,江苏连云港,222001 3. 天津红日药业股份有限公司,天津,301700 |
| 摘 要： | 目的:优选葛根中异黄酮的提取工艺.方法:以葛根异黄酮为评价指标,通过响应面分析法优化葛根异黄酮的提取工艺,并对最佳提取工艺进行工艺验证.结果:葛根异黄酮的最佳提取工艺为65％乙醇,超声提取28 min,料液比1∶29,异黄酮的提取率可达4.87％.结论:采用响应面分析法优化对葛根异黄酮提取条件进行优化合理可行. |
| 关 键 词： | 响应面 葛根 异黄酮 提取工艺 |
| 收稿时间： | 2011/4/13 0:00:00 |
Optimization of Extraction Technology of Isoflavones from Pueraria lobata by Response Surface Analysis Methodology |
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| WANG Yan-yan,WANG Tuan-jie and DING Lin-lin.Optimization of Extraction Technology of Isoflavones from Pueraria lobata by Response Surface Analysis Methodology[J].China Journal of Experimental Traditional Medical Formulae,2012,18(2):45-48. | |
| Authors: | WANG Yan-yan WANG Tuan-jie and DING Lin-lin |
| Institution: | Lianyungang Branch of Traditional Chinese Medicine, Jiangsu Union Technical Institute, Lianyungang 222006, China;Jiangsu Kanion Pharmaceutical Co. Ltd, Lianyungang 222001 China;Tianjin Chasesun Pharmaceutical Co. Ltd, Tianjin 301700, China |
| Abstract: | Objective:To optimize of extraction technology for isoflavones from Pueraria lobata.Method:Optimization of extraction technology for isoflavones from P.lobata by response surface analysis method with isoflavones from P.Lobata as index,and verification of optimum extraction technology.Result:Optimal extraction technology was as follows: ethanol concentration 65%,ultrasonic extraction time 28 min,solid-liquid ratio 1∶29,extraction ratio of isoflavones could be up to 4.87%.Conclusion:It was feasible to optimize extraction processing of isoflavones from P.lobata by response surface analysis methodology. |
| Keywords: | response surface methodology Pueraria lobata isoflavones extraction technology |
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