| Synergism of atenoloi and nitrendipine on hemodynamic amelioration and organ protection in hypertensive rats |
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| 摘 要： | OBJECTIVE： This study was designed to investigate the possible synergism of atenolol and nitrendipine on blood pressure （BP） and blood pressure variability （BPV） reductions, baroreflex sensitivity （BRS） amelioration, and organ protection in hypertensive rats. METHOD： The dose was 20 mg/kg for atenolol, 10 mg/kg for nitrendipine and 20 ＋ 10 mg/kg for the combination of these two drugs. In an acute study, a single dose was given via a catheter previously inserted into the stomach in spontaneously hypertensive rats （SHR）.
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| 关 键 词： | 协同作用 尼群地平 血液动力学 高血压 |
Synergism of atenoloi and nitrendipine on hemodynamic amelioration and organ protection in hypertensive rats |
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| Xie HH, Miao CY, Jiang YY, Su DF. Synergism of atenoloi and nitrendipine on hemodynamic amelioration and organ protection in hypertensive rats[J]. Former Academic Journal of Second Military Medical University, 2006, 27(2): 164-164 |
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| Authors: | Xie HH Miao CY Jiang YY Su DF |
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