| 老年冠心病患者氧化修饰低密度脂蛋白与微量元素代谢变化的关系 |
| |
| 引用本文： | 田庆印,平雨华,潘其兴,邹明瑾.老年冠心病患者氧化修饰低密度脂蛋白与微量元素代谢变化的关系[J].中国老年学杂志,1999,19(2):76-78. |
| |
| 作者姓名： | 田庆印 平雨华 潘其兴 邹明瑾 |
| |
| 作者单位： | 1. 山东医科大学附属医院心内科,济南,250012
2. 成武县医院内科 |
| |
| 摘 要： | 目的探讨老年冠心病患者机体微量元素代谢与低密度脂蛋白氧化之间的关系。方法测定６０例老年冠心病患者及３６例正常人血浆氧化低密度脂蛋白（ＯＸ－ＬＤＬ）水平，同时测定血清锌、硒、铜等１３种元素及血清铜蓝蛋白（ＣＰ）、铁蛋白（ＳＦ）、脂质、脂蛋白等。各检测指标与ＯＸ－ＬＤＬ行直线相关分析及多因素逐步回归分析。结果冠心病组血浆ＯＸ－ＬＤＬ、血清ＴＧ、ＬＤＬ－Ｃ、铜、ＣＰ、ＳＦ、铜／锌水平均显著高于正常对照组，血清硒、锌、ＨＤＬ－Ｃ、铬水平均显著低于正常对照组。ＴＧ、铜、ＣＰ、铜／锌与ＯＸ－ＬＤＬ呈显著正相关，而ＨＤＬ－Ｃ、硒、锌与ＯＸ－ＬＤＬ呈显著负相关。多因素逐步回归分析表明硒、锌、铜、铁等微量元素可影响低密度脂蛋白的氧化。结论铁、铜可能促进体内ＯＸ－ＬＤＬ的形成，而硒、锌对低密度脂蛋白的氧化可能起保护作用。
|
| 关 键 词： | 冠心病 微量元素 氧化低密度脂蛋白 |
Relationship between oxidized low density lipoprotein and trace elements metabolism in patients with coronary heart disease |
| |
| Lin
Guangzhu,Wu Qiao,Jiang Hongyu et al the First Teaching Hospita,Normane Bethune University
of Medical Sciences,Changchun Objective\.Relationship between oxidized low density lipoprotein and trace elements metabolism in patients with coronary heart disease[J].Chinese Journal of Gerontology,1999,19(2):76-78. |
| |
| Authors: | Lin
Guangzhu Wu Qiao Jiang Hongyu the First Teaching Hospita Normane Bethune University
of Medical Sciences Changchun Objective\ |
| |
| Institution: | Lin
Guangzhu,Wu Qiao,Jiang Hongyu et al the First Teaching Hospita,Normane Bethune University
of Medical Sciences,Changchun 130021 Objective\ |
| |
| Abstract: | The leveel of SIl 2R of the
elderly hypertensive patients were studied according to the clinical stages.Methods ELISA were
used to determine the sIL 2R of the hypertensives ( n =46) and compared with that control
group ( n=30 ).Results The levels of sIL 2R in hypertensive elderly were higher than that of
NC( P <0.01);and increase with the advancing of clinical stages( P <0.01).Conclusions\ The
immune function disorders in the hypertensive elderly resulted with abnormal sIL 2R,so that,
sIL 2R could be a valid index of cell immune function of the elderly hypertensive patients. |
| |
| Keywords: | Hypertension in gerontal patient\ sIL 2R\ Clinical stage |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
