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恶性肿瘤患者血清Kappa与Lambda轻链检测及临床意义
引用本文:姚弘,林永财,张忠英. 恶性肿瘤患者血清Kappa与Lambda轻链检测及临床意义[J]. 国际检验医学杂志, 2000, 30(2): 562-563. DOI: 10.3760/cma.j.issn.1673-4130.2009.06.014
作者姓名:姚弘  林永财  张忠英
作者单位:厦门大学附属中山医院检验科,福建厦门,361004;
摘    要:Objective To investigate the abnormal expressions of immunoglobulin light chains kappa(Igκ)and Lambda(Igλ)in malignant tumors.Methods The concentrations of the Igκ and Igλ in serum were measured by rat nephelometry in 60 cases of malignant tumors and 15 cases of healthy people.Results The liver tumor patients had a higher concentration of Igκ and Igλ in serum than normal people(P<0.01).There wre not significant differences between the levels of Igκ,Igλ and κ/λ ratio in the stomach tumor,lung tumor,proctologic/colonic tumor,mammary tumor,oesophagus tumor and normal peoples(P>0.05).Conclusion The measurment of Igκ,Igλ and κ/λ ratio in serum would be helpful for the diagnosis of the liver tumor.By continous observation with Igκ,Igλ and κ/λratio in serum could predict the development of disease.

关 键 词:肿瘤   免疫球蛋白轻链   散射测浊法和比浊法   

The abnormal expressions of immunoglobulin light chains Kappa and Lambda in malignant tumors
YAO Hong,LIN Yong-ai,ZHANG Zhong-ying. The abnormal expressions of immunoglobulin light chains Kappa and Lambda in malignant tumors[J]. International Journal of Laboratory Medicine, 2000, 30(2): 562-563. DOI: 10.3760/cma.j.issn.1673-4130.2009.06.014
Authors:YAO Hong  LIN Yong-ai  ZHANG Zhong-ying
Abstract:
Keywords:NeoplasmsImmunoglobulin light chainsNephelometry and turbidimetry
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