Primary Immunodeficiency Diseases in Latin America: First Report from Eight Countries Participating in the LAGID |
| |
Authors: | Marta Zelazko Magda Carneiro-Sampaio Monica Cornejo De Luigi Diana Garcia De Olarte Oscar Porras Madrigal Renato Berrón Perez Agueda Cabello Marylin Valentin Rostan Ricardo U. Sorensen |
| |
Affiliation: | (1) National Pediatric Hospital Juan P. Garrahan, Buenos Aires, Argentina;(2) Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil;(3) University of Valparaiso, Valparaiso, Chile;(4) University of Antioquia, Medellin, Colombia;(5) Immunology Service, National Children's Hospital Dr. Carlos Saenz Herrera, San Jose, Costa Rica;(6) Immunology Service, National Institute of Pediatrics, Mexico City, Mexico;(7) Institute for Health Science Research, National University of Rio dela Plata and Lagerenza, Asunción, Paraguay;(8) Pigalle Clinic, Montevideo, Uruguay;(9) Department of Pediatrics, LSU Medical Center, New Orleans, Louisiana, 70112-2822 |
| |
Abstract: | The Latin American Group for Primary Immunodeficiencies, formed in 1993, presently includes 12 countries. One goal was to study the frequency of primary immunodeficiencies in various regions of the American continent and to enhance knowledge about these diseases among primary-care physicians, as well as allergist–immunologists. Important for this purpose was the development of a registry of primary immunodeficiencies using a uniform questionnaire and computerized database. To date, eight countries have collected information on a total of 1428 patients. Predominantly antibody deficiencies were reported in 58% of patients, followed by cellular and antibody immunodeficiencies associated with other abnormalities in 18%, immunodeficiency syndromes associated with granulocyte dysfunction in 8%, phagocytic disorders in 9%, combined cellular and antibody immunodeficiencies in 5%, and complement deficiencies in 2% of patients. The information gathered from this initial analysis of data will serve to expand the patient database to more areas within participating countries and to new countries and to increase collaboration toward better diagnosis and treatment of these diseases. |
| |
Keywords: | Primary immunodeficiencies registry Latin America |
本文献已被 SpringerLink 等数据库收录! |
|