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p16蛋白在维吾尔族妇女宫颈癌组织中的表达及意义
引用本文:海力曼·依拉洪,米开热木·麦麦提,海米提·阿布都力木. p16蛋白在维吾尔族妇女宫颈癌组织中的表达及意义[J]. 新疆医科大学学报, 2007, 30(6): 599-600,603
作者姓名:海力曼·依拉洪  米开热木·麦麦提  海米提·阿布都力木
作者单位:1. 新疆医科大学基础医学院病理教研室,新疆,乌鲁木齐,830054
2. 喀什地区第一人民医院病理科,新疆,喀什,844000
3. 新疆医科大学基础医学院组胚教研室,新疆,乌鲁木齐,830054
摘    要:目的:研究p16蛋白在维吾尔族宫颈癌组织中的表达及其意义。方法:采用免疫组化二步法检测50例正常宫颈组织和93例宫颈癌组织中p16蛋白的表达。结果:维吾尔族宫颈癌及正常宫颈组织中p16蛋白的阳性表达率与汉族均无统计学差异(P均〉0.05);但维吾尔族、汉族宫颈癌p16蛋白阳性表达率明显高于维吾尔族、汉族正常宫颈组织(P〈0.05)。结论:p16蛋白表达可作为诊断宫颈癌的辅助指标。

关 键 词:宫颈癌  免疫组织化学  维吾尔族
文章编号:1009-5551(2007)06-0599-03
修稿时间:2006-12-20

The expression and significance of protein p16 in cervical cancer tissue of Uighur women
Hailiman·Yilahong,Mikeremu·Maimaiti,Haimiti·Abudulimu. The expression and significance of protein p16 in cervical cancer tissue of Uighur women[J]. Journal of Xinjiang Medical University, 2007, 30(6): 599-600,603
Authors:Hailiman·Yilahong  Mikeremu·Maimaiti  Haimiti·Abudulimu
Affiliation:Department of Pathology, Xinjiang Medical University , Urumqi 830054, China
Abstract:Objective:To study the expression and significance of protein p16 in cervical cancer tissues of Uighur women.Methods:An immunohistochemistry method was used to detect the expression of protein p16 in 50 normal cervical tissues and 93 cervical cancer tissues.Results:The expressions of protein p16 in the normal cervical tissues and cervical cancer tissues of Han nationality and Uighur had no statistical significance(P>0.05),respectively.The expression of p16 btween cervical cancer tissues and normal tissues of Han nationality and Uighur had statistical significances(P<0.05),respectively.Conclusion:The p16 expression could be as an diagnostic index in cervical cancer.
Keywords:p16
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