| 顶空气相色谱法测定甲磺酸帕珠沙星中有机溶剂残留量 |
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| 引用本文： | 蔡振华,蒋庆峰. 顶空气相色谱法测定甲磺酸帕珠沙星中有机溶剂残留量[J]. 中国药业, 2007, 16(1): 15-16 |
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| 作者姓名： | 蔡振华 蒋庆峰 |
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| 作者单位： | 天津药物研究院分析测试中心,天津,300193 |
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| 摘 要： | 目的 建立顶空进样气相色谱法检测甲磺酸帕珠沙星中5种有机溶剂残留量的方法。方法 采用顶空程序升温气相色谱法，顶空平衡温度100℃，平衡时间20min，色谱柱为DM-624毛细管柱（30．0m×0．53min×3．00ιμm），柱温初始为50℃，保持3min后以20℃／min的速率升温到200℃，保持2min。结果 甲醇、乙醇、乙酸乙酯、二氧六环、二甲基甲酰胺5种有机溶剂在该试验条件下可同时测定。结论 该法操作简单，结果准确、可靠。
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| 关 键 词： | 顶空进样气相色谱法 甲磺酸帕珠沙星 有机溶剂残留 |
| 文章编号： | 1006-4931（2007）01-0015-02 |
| 收稿时间： | 2006-06-26 |
| 修稿时间： | 2006-06-26 |
Headspace GC Determination of Residual Organic Solvents in Pazufloxacin Mesylas |
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| Cai Zhenhua,Jiang Qingfeng. Headspace GC Determination of Residual Organic Solvents in Pazufloxacin Mesylas[J]. China Pharmaceuticals, 2007, 16(1): 15-16 |
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| Authors: | Cai Zhenhua Jiang Qingfeng |
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| Affiliation: | Cai Zhenhua, Jiang Qingfeng ( Tianjin Institute of Pharmaceutical Research, Tianjin, China 300193) |
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| Abstract: | Objective To establish a method for determing the residual organic s olvents in pazufloxacin mesylas.Methods The residual organic solvents were quant itatively determined by temperature programmed headspace GC.The capillary column was DM-624.Results There was a good linear relation in the experimental concen tration.Conclusion The proposed method is easily operative and simple,accurate a nd rapid with good sensitivity. |
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| Keywords: | headspaee GC pazufloxacin mesylas residual organic solvents |
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