A novel HLA-DRB1 allele, DRB1*1219, was identified by sequence-based typing in a Chinese leukaemia family |
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| Authors: | X.-M. Nie,Y.-H. Fang,Y. Zhang,W.-D. He,& C.-F. Zhu |
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| Affiliation: | HLA Laboratory, Blood Center of Shandong Province, Jinan, Shandong Province, China |
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| Abstract: | A novel human leukocyte antigen DRB1 allele, DRB1*1219, has been identified in a Chinese leukaemia patient and his family by polymerase chain reaction sequence-based typing, which has one nucleotide change at position 341 (C→T) in exon 2 from the closest matching allele DRB1*120201, resulting in an amino acid substitution from Ala→Val at codon 85. |
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| Keywords: | DRB1*1219 human leukocyte antigen novel allele sequence-based typing |
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