Daily movement patterns and predicted 10-yr risk for a first atherosclerotic cardiovascular disease (ASCVD) event using the pooled cohort risk equations among US adults |
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| Institution: | 1. Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA;2. Technical Unit for Social Determinants and Risk Factors for Chronic Diseases and Mental Health, Pan-American Health Organization, Brasilia, Brazil;3. Department of Health Management and Informatics, School of Medicine, University of Missouri-Columbia, Columbia, MO, USA;4. Program in Physical Therapy & Department of Surgery (Prevention), Washington University in St. Louis School of Medicine, St. Louis, MO, USA;5. Prevention Research Center in St. Louis, Brown School, Washington University in St. Louis, St. Louis, MO, USA;6. Division of Public Health Sciences and Alvin J. Siteman Cancer Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA;1. Tobacco Control Research Branch, National Cancer Institute, Rockville, MD, United States;2. Center for Tobacco Products, Food and Drug Administration, Silver Spring, MD, United States;1. Division of Family Medicine, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden;2. Academic Primary Healthcare Centre, Stockholm County Council, Huddinge, Sweden;3. Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden;4. Public Healthcare Services Committee Administration, Stockholm County Council, Box 6909, SE-102 39 Stockholm, Sweden;5. Medical Management Centre, Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Berzelius väg 3, SE-17177 Stockholm, Sweden;1. Department of Epidemiology, Health Economics and Public Health, UMR1027 INSERM–Toulouse University, Toulouse University Hospital (CHU), Toulouse, France;2. Department of Epidemiology and Public Health, INSERM UMR744, Pasteur Institute of Lille, Lille Nord de France University–UDSL, Lille, France;3. Department of Epidemiology and Public Health, EA 3430, FMTS, Strasbourg University, Strasbourg, France;4. Department of Public Health, Strasbourg University Hospital, Strasbourg, France;5. Department of Cardiology B, Toulouse University Hospital, Toulouse, France;1. Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States;2. MacDiarmid Institute for Advanced Materials and Nanotechnology, Department of Electrical and Computer Engineering, University of Canterbury, Christchurch, New Zealand;3. Department of Dermatology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States;1. Office on Smoking and Health, US Centers for Disease Control and Prevention, Atlanta, GA, USA;2. Center for Global Health, US Centers for Disease Control and Prevention, Atlanta, GA, USA;3. Office of Tobacco Control, Chinese Center for Disease Control and Prevention, Beijing, PR China |
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| Abstract: | ObjectiveExamine the association between movement patterns and predicted risk of a first atherosclerotic cardiovascular disease (ASCVD) event.MethodsData from the 2003–2006 National Health and Nutrition Examination Survey (NHANES) were used (40–79 yrs; N = 2421). Participants wore an ActiGraph 7164 accelerometer to create four movement pattern groups; Group 1: ≥ 150 min/wk of moderate-to-vigorous physical activity (MVPA) and light-intensity physical activity (LIPA) ≥ sedentary behavior (SB); Group 2: ≥ 150 min/wk of MVPA and LIPA < SB; Group 3: < 150 min/wk of MVPA and LIPA ≥ SED; and Group 4: < 150 min/wk of MVPA and LIPA < SB. 10-yr risk for a first ASCVD event was estimated using the pooled cohort equations.ResultsAfter adjusting for age, gender, race–ethnicity and obesity, Group 2 (β = ? 0.28; p = 0.44) was not significantly different than Group 1, but Groups 3 (β = 1.09; p = 0.01) and 4 (β = 1.44; p < 0.001) had a higher pooled risk score.ConclusionsThose in the least desirable movement pattern (Group 4) had the highest pooled risk score. Given the similar risk scores for Groups 1 and 2, future research is needed to determine if sufficient MVPA can counteract the potential consequences associated with an imbalanced LIPA:SB ratio (i.e., LIPA < SB). |
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