Aggressive fibromatosis of the right colon mimicking a gastrointestinal stromal tumour: a case report |
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| Authors: | Milica Mitrovic Jovanovic Aleksandra Djuric-Stefanovic Dejan Velickovic Ebrahimi Keramatollah Marijan Micev Aleksandra Jankovic Stefan Milosevic Jelena D Kovac |
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| Institution: | 1.Centre for Radiology and MRI, University Clinical Centre of Serbia, Belgrade, Serbia; 2.Clinic for Digestive Surgery, University Clinical Centre of Serbia, Belgrade, Serbia; 3.Faculty of Medicine, University of Belgrade, Belgrade, Serbia; 4.Institute of Pathology, University Clinical Centre of Serbia, Belgrade, Serbia |
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| Abstract: | Aggressive fibromatosis is a rare type of intra-abdominal desmoid tumour that usually involves the small bowel mesentery. It is a locally-invasive lesion, with a high rate of recurrence, but without metastatic potential. Aggressive fibromatosis is seen more often in young female patients. This case report presents the radiological, intraoperative and histopathological findings from a 37-year-old female patient that presented with epigastric pain and a palpable mass in the right hemiabdomen. Histological and immunohistochemical examinations of the resected tumour, including positive staining for beta-catenin, confirmed a postoperative diagnosis of desmoid type fibromatosis. This specific case showed that desmoid type fibromatosis of the colon can mimic gastrointestinal stromal tumours (GIST) based on its clinical presentation, computed tomography and magnetic resonance imaging findings. Differential diagnosis between desmoid type fibromatosis and GIST is clinically very important due to the different treatments and follow-up protocols that are implemented for these lesions. |
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| Keywords: | Aggressive fibromatosis gastrointestinal stromal tumour computed tomography magnetic resonance imaging |
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