Role of Vitamin D in the Metabolic Syndrome |
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Authors: | Lucía Melguizo-Rodríguez Víctor J Costela-Ruiz Enrique García-Recio Elvira De Luna-Bertos Concepcin Ruiz Rebeca Illescas-Montes |
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Institution: | 1.Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain; (L.M.-R.); (V.J.C.-R.); (E.G.-R.); (E.D.L.-B.); (R.I.-M.);2.Instituto Investigación Biosanitaria, ibs.Granada, 18012 Granada, Spain;3.Institute of Neuroscience, University of Granada, 18016 Granada, Spain |
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Abstract: | The prevalence of hypovitaminosis D has risen in developed countries over the past few years in association with lifestyle changes and an increase in unhealthy habits. Vitamin D deficiency has been implicated in various diseases, including metabolic syndrome (MetS), which is clinically defined by a set of metabolic and vascular disorders. The objective of this study was to review scientific evidence on the relationship between MetS and vitamin D deficiency to support the development of prevention strategies and health education programs. An inverse relationship has been reported between plasma vitamin D concentrations and the features that define MetS, i.e., elevated serum concentrations of glucose, total cholesterol, low-density lipoproteins, triglycerides, glycosylated hemoglobin, and a high body mass index. Numerous studies have described the benefits of vitamin D supplementation to improve outcomes in individuals with MetS. Interventions to maintain optimal vitamin D concentrations are proposed as a preventive strategy against MetS. |
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Keywords: | metabolic syndrome vitamin D cardiovascular risk diabetes mellitus obesity insulin resistance |
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