汉、维吾尔族神经症患者视觉事件相关电位P300对比研究

目的：探讨汉族与维吾尔族神经症患者视觉事件相关电位P300的异同。方法：选97例神经症患者作为神经症组（汉族48例,维族49例）,99例健康者作为对照组（汉族45例,维族47例）,对所有入组者均进行视觉事件相关电位P300检测并比较。结果：两组中汉族和维吾尔族神经症患者的靶N2潜伏期、靶P3潜伏期及波幅、非靶P2波幅差异均无统计学意义（P均〉0.05）;与正常对照组比较,汉族与维吾尔族神经症患者的靶N2潜伏期均延长（P均〈0.05）,靶P3潜伏期均延长且波幅降低（P均〈0.05）,非靶P2波幅均降低（P〈0.05）。结论：汉族与维吾尔族神经症患者的视觉事件相关电位P300差异无统计学意义;神经症患者的视觉事件相关电位P300有多项指标变化。

Comparison of the visual event-related potential P300 between the Han and the Uighur patients with neurosis

Objective： To compare the visual event-related potential P300 between the Han and the Uighur patients with neurosis. Method： 97 cases of neurosis patients （48 Han and 49 Uighur） were served as neurosis group,and 99 healthy adults （45Han and 47 Uighur） as control group. The visual event-related potential P300 was tested in all the people. Results： The Han and Uighur people showed no significant differences in latencies of target N2,target P3 and amplitudes of target P3,non-target P2 in both the neurosis group and control group （all P 0. 05） . Compared with the control group,the latencies of target N2、target P3 were prolonged significantly and amplitudes of target P3,non-target P2 were reduced significantly in the neurosis group （all P 0. 05） . Conclusion： There are no significant differences in visual event-related potential P300 between the Han and Uighur patients with neurosis,but the neurosis patients were different on visual event-related potential P300 indices from normal.