妊娠期肝内胆汁淤积症85例临床研究

目的　研究分析妊娠期肝内胆汁淤积症 (ICP)患者肝功能指标与ICP围产儿预后关系。方法　对 85例ICP患者进行了回顾性临床分析。结果　ICP患者肝功能胆汁酸 (TBA)、血清谷丙转氨酶 (SGPT)、总胆红素 (TBIL)水平越高 ,则胎儿窘迫、羊水污染、新生儿窒息的发生率就愈高 (P <0 0 1) ,新生儿平均体重就轻。结论　对ICP患者进行肝功能部分指标的检测 ,是监测胎儿预后的一项可靠指标 ,在妊娠中晚期对产前母婴保健工作有十分重要意义

Clinical Analysis of 85 Cases with Intrahepatic Cholestasis of Pregnancy

Objective To analyse the relationship between hepatic function index and perinatal-prognosis in patients with the intrahepatic cholestasis of pregnancy(ICP). Methods The clinical data of 85 the patients with ICP in our department were retrospectively reviewed. Results The more the serum levels of TBA,SGPT and TBIL in the patients with ICP were, the more incidence of fetal distress, amniotic fluid contamination and asphyxia neonatorum would be (P<0 01). Conclusion The hepatic function of the patients with ICP is a dependable index for monitoring perinatal-prognosis,and the hepatic function test has an important significance for health protection of mother and fetus.