重症监护病房院内感染病原菌分析

目的：探讨重症监护病房院内感染病原菌的分布与耐药情况。方法：对我院2009年1月至2012年6月重症监护病房内发生院内感染的195例患者进行感染致病菌分离鉴定，并通过药敏试验分析细菌耐药情况。结果：195例重症监护病房医内感染患者的送检样本中，共分离获得390株病原菌，其中比例最高的菌株为铜绿假单胞菌，占39．49％，其次为肺炎克雷伯菌，占22．82％。病原菌以革兰氏阴性．杆菌为主，革兰氏阳性．球菌仅占2．82％。革兰氏阴性．杆菌呈现多重耐药，对亚胺培南具有高度耐药性；而鲍曼不动杆菌对所有抗菌药物均具存在耐药现象，铜绿假单胞菌和大肠埃希菌均对氨苄青霉素无耐药现象。结论：分析重症监护病房院内感染病原菌的分布特点与耐药情况对正确指导临床用药，防止抗菌药滥用，减少细菌耐药发展具有重要的作用。

Analysis on Pathogenic Bacteria of Nosocomial Infection in ICU

Objective： To analyze the distribution and drug resistance of pathogenic bacteria of nosoeo- mial infection in ICU nosocomial. Method： 195 patients occing nosoeomial infection pathogens in ICU from January 2009 to June 2012 in our hospital were given isolation and identification of infection pathogenic bacteria. And analyzed bacterial drug resistance through drug sensitivity test. Result： Among the censored sample of 195 patients with nosocomial infection pathogens in ICU nosocomial, 390 strains of pathogens were classified. The highest proportion of strains was pseudomonas aeruginosa accounting for 39.49%, followed by Klebsiella pneumoniae accounting for 22.82%. Pathogenic bacteria gave priority to gram negative bacillus accounting for only 2.82%. Gram negative bacillus presents multiple resistance, which has a high degree of resistance to imipenem. But bauman acinetobacter has drug- resistant phenomenon on all antimicrobial drugs. Pseudomonas aeruginosa and escherichia coli has no drug-resistant phenomenon on ampicillin. Conclusion： Analyzing the distribution characteristics and drug resistance of nosocomial infection pathogens in ICU nosocomial plays an important role in guiding the clinical treatment, preventing antibiotics abuse and reducing bacterial drug resistance.