| 紫外线照射后哺乳动物细胞DNA的期外合成 |
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| 引用本文： | 刘学英,李惠敏,魏康. 紫外线照射后哺乳动物细胞DNA的期外合成[J]. 军事医学科学院院刊, 1986, 0(3) |
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| 作者姓名： | 刘学英 李惠敏 魏康 |
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| 作者单位： | 军事医学科学院放射医学研究所(刘学英，李惠敏)，军事医学科学院放射医学研究所(魏康) |
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| 摘 要： | 本实验用~3H-TdR掺入,液体闪烁测量法测定细胞DNA期外合成的方法,测定了小鼠和大鼠的肠淋巴结细胞、人和大鼠外周血淋巴细胞、S-180V肿瘤细胞等经紫外线照射后的UDS,观察到UDS掺入量随辐照度增加而增加。在同一辐照剂量下,以小鼠肠淋巴结细胞的UDS值最高,其次是人外周血淋巴细胞和S-180V肿瘤细胞,而大鼠外周血淋巴细胞和肠淋巴结细胞最低。
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| 关 键 词： | DNA期外合成 DNA修复 紫外线照射 |
UNSCHEDULED DNA SYNTHESIS INDUCED BY ULTRAVIOLET RADIATION IN MAMMALIAN CELLS |
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| Liu Xueying,Li Huimin,Wei Kang Institute of Radiation Medicine. UNSCHEDULED DNA SYNTHESIS INDUCED BY ULTRAVIOLET RADIATION IN MAMMALIAN CELLS[J]. Bulletin of the Academy of Military Medical Sciences, 1986, 0(3) |
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| Authors: | Liu Xueying Li Huimin Wei Kang Institute of Radiation Medicine |
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| Affiliation: | Liu Xueying;Li Huimin;Wei Kang Institute of Radiation Medicine |
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| Abstract: | Unscheduled DNA Synthesis(UDS)implies the repair ability of damaged cell.UDS of lymphocytes from intestine lymph node of mice and rats,rat and human blood lymph-ocytes and S-180(?) tumor cells was observed after UV radiation.The amount of UVradiation-induced UDS of the lymphocytes and S-180(?) tumor cells was proportional tothe doses of UV irradiation.After UV radiation,UDS of lymphocytes from mesentericlymph node of mice was most intensive,whereas UDS of lymphocytes from blood andmesenteric lymph node of rats was least. |
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| Keywords: | unscheduled DNA synthesis(UDS) DNA repair UV irradiation |
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