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Too Fit To Fracture: exercise recommendations for individuals with osteoporosis or osteoporotic vertebral fracture
Authors:L. M. Giangregorio  A. Papaioannou  N. J. MacIntyre  M. C. Ashe  A. Heinonen  K. Shipp  J. Wark  S. McGill  H. Keller  R. Jain  J. Laprade  A. M. Cheung
Affiliation:1. Department of Kinesiology, University of Waterloo, 200 University Ave, Waterloo, ON, N2L 3G1, Canada
2. University Health Network, Toronto Rehabilitation Institute, Toronto, Canada
3. Schlegel-UW Research Institute for Aging, Kitchener, Canada
4. Department of Medicine, McMaster University, Hamilton, Canada
5. School of Rehabilitation Science, McMaster University, Hamilton, Canada
6. Department of Family Practice, University of British Columbia, Vancouver, Canada
7. Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland
8. Department of Community and Family Medicine, Duke University, Durham, NC, USA
9. Department of Medicine, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia
10. Osteoporosis Canada, Toronto, Canada
11. Division of Anatomy, University of Toronto, Toronto, Canada
12. Department of Medicine, University Health Network, University of Toronto, Toronto, Canada
Abstract:

Summary

A consensus process was conducted to develop exercise recommendations for individuals with osteoporosis or vertebral fractures. A multicomponent exercise program that includes balance and resistance training is recommended.

Introduction

The aim was to develop consensus on exercise recommendations for older adults: (1) with osteoporosis and (2) with osteoporotic vertebral fracture(s).

Methods

The Grading of Recommendations Assessment, Development, and Evaluation method was used to evaluate the quality of evidence and develop recommendations. Outcomes important for decision making were nominated by an expert panel and patient advocates. They included falls, fractures, bone mineral density (BMD), and adverse events for individuals with osteoporosis/vertebral fractures, and pain, quality of life, and function for those with vertebral fracture. Meta-analyses evaluating the effects of exercise on the outcomes were reviewed. Observational studies or clinical trials were reviewed when meta-analyses were not available. Quality ratings were generated, and informed the recommendations.

Results

The outcome for which evidence is strongest is falls. Point estimates of the effects of exercise on falls, fractures, and BMD vary according to exercise type. There is not enough evidence to quantify the risks of exercise in those with osteoporosis or vertebral fracture. Few trials of exercise exist in those with vertebral fracture. The exercise recommendations for exercise in individuals with osteoporosis or osteoporotic vertebral fracture are conditional. The panel strongly recommends a multicomponent exercise program including resistance and balance training for individuals with osteoporosis or osteoporotic vertebral fracture. The panel recommends that older adults with osteoporosis or vertebral fracture do not engage in aerobic training to the exclusion of resistance or balance training.

Conclusions

The consensus of our international panel is that exercise is recommended for older adults with osteoporosis or vertebral fracture, but our recommendations are conditional.
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