| HPLC—ELSD测定克拉霉素胶囊的含量 |
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| 引用本文： | 袁步娟,邰顺章. HPLC—ELSD测定克拉霉素胶囊的含量[J]. 中国实用医药, 2009, 4(25): 3-4 |
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| 作者姓名： | 袁步娟 邰顺章 |
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| 作者单位： | 江苏省盐城药品检验所,224002 |
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| 摘 要： | 目的研究克拉霉素胶囊的含量测定方法。方法用高效液相色谱．蒸发光散射检测法进行含量测定。结果该方法能很好分离被测组分与其他杂质，在实验浓度范围内峰面积的对数值与浓度的对数值呈良好的线性关系，r=0．9998，RSD=0．36％。结论用高效液相色谱-蒸发光散射检测法测定克拉霉素胶囊的含量，方法简便，结果准确。
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| 关 键 词： | 克拉霉素胶囊 含量测定 HPLC-ELSD |
HPLC-ELSD Determination of Content of Clarithromycin Capsules |
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| YUAN Bu-juan,TAI Shun-zhang. HPLC-ELSD Determination of Content of Clarithromycin Capsules[J]. China Practical Medical, 2009, 4(25): 3-4 |
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| Authors: | YUAN Bu-juan TAI Shun-zhang |
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| Affiliation: | YUAN Bu-juan, TM Shun-zhang. (Yancheng Drug Inspection, Yanchen 224002, China) |
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| Abstract: | Objective To develop a method for the determination of clarithromycin capsule. Methods Using high performance liquid chromatography （HPLC） -evaporative light scattering Detector assay for content determination. Results This method can be measured with other components were separated in the experi- ment, the concentration of impurity peak area within the scope of the concentration of numerical value and a good linear relationship, r = 0. 9998, RSD = 0. 36%. Conclusion Using HPLC-ELSD assays the content determination of elarithromycin capsule, the method is simple and accurate. |
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| Keywords: | HPLC-ELSD |
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