| 通阳利尿散对Heymann肾炎大鼠的药理作用 |
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| 引用本文： | 张宾,孙曙光,张董喆. 通阳利尿散对Heymann肾炎大鼠的药理作用[J]. 河南中医学院学报, 2008, 23(3): 19-20 |
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| 作者姓名： | 张宾 孙曙光 张董喆 |
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| 作者单位： | 河南中医学院 河南郑州450008 |
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| 基金项目： | 河南中医学院校科研和教改项目 |
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| 摘 要： | 目的:观察通阳利尿散对被动型Heymann肾炎(Passive Heymann Nephritis,PHN)大鼠的药理作用。方法:以大鼠肾脏皮质匀浆和弗氏完全佐剂制成同种免疫复合物,对同种大鼠诱发PHN,观察通阳利尿散对PHN大鼠的尿肌酐、尿蛋白及血清总蛋白、肌酐和尿素氮的作用。结果:通阳利尿散能显著降低被动型Heymann肾炎模型大鼠尿蛋白、血清肌酐和尿素氮水平,升高血清总蛋白含量。结论:通阳利尿散能改善肾功能。
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| 关 键 词： | 通阳利尿散 被动型Heymann肾炎 药理作用 大鼠 |
| 文章编号： | 1672-6839(2008)03-0019-02 |
| 修稿时间： | 2008-03-06 |
Effect of Tongyangliniao Powder on Passive-heymann Nephritis Nephritis in Rat |
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| Zhang Bin,Sun Shuguang,Zhang Dongzhe. Effect of Tongyangliniao Powder on Passive-heymann Nephritis Nephritis in Rat[J]. Journal of Henan University of Chinese Medicine, 2008, 23(3): 19-20 |
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| Authors: | Zhang Bin Sun Shuguang Zhang Dongzhe |
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| Abstract: | Objective: To study the pharmacological actions of Tongyangliniao Powder(TYP) on experimental Passive-Heymann Nephritis(PHN)model rats. Methods: The rat model of PHN Was induced by injecting immune complexes with renal cortical tissue and Freund's adjuvant Complete. The renal function about urinary protein, serum total protein,creatinine and urinary nitrogen on PHN rat were studied.Results: TYP can remarkably reduce urinary protein,serum levels of serum creatinine and serum urinary nitrogen, increase serum total protein content. Conslusion: TYP can ameliorate the renal function. |
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| Keywords: | Tongyangliniao Powder Passive-Heymann Nephritis model pharmaeoligieal actions rats |
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