3种治疗方案根除幽门螺杆菌的药物经济学评价

目的 探讨不同药物治疗方案根除幽门螺杆菌的药物经济学评价。方法根据文献选择Hp阳性感染患者122例，随机分为A、B、C3组，分别给予羟氨苄青霉素 呋喃唑酮 兰索拉唑 胶体果胶铋(A)、羟氨苄青霉素 呋喃唑酮 胶体果胶铋(B)和羟氨苄青霉素 呋喃唑酮 兰索拉唑(C)，运用药物经济学的成本-效果分析方法进行分析评价。结果3种药物治疗方案总成本依次为603．90元、458．90元、513．90元，Hp的根除率依次为92．7％、82．5％、85．4％。结论A组方案为根除Hp的最佳方案。

Pharmacoeconomic Evaluation on The Eradication of Helicobacter Pylori Infection with Three Kinds of pharmacotherapeutic schemes

Objective To discuss the economical effects of different medications on the treatment of same illness.Methods According to literature reports,122cases with Helicobacter pylori (Hp) infection were selected.These patients were randomly divided into three groups.Amoxicillin and furazolidone and lansoprazole and colloidal bismuth pectin was given to A,Amoxicillin and furazolidone and lansoprazole was given to B.Amoxicillin and furazolidone and colloidal bismuth pectin was given to C.Data was evaluated using the pharmacoeconomic cost-effectiveness analysis.Results The costs of the three pharmacotherapeutic schemes were RMB 603.90,458.90,513.90 yuans,respectively.The eradication rates of Hp were 92.7%,82.5%,85.4%,respectively.Conclusion A is the best effective and inexpensive scheme to eradicate Hp.